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Integration of Human Protein Sequence and Protein-Protein Interaction Data by Graph Autoencoder to Identify Novel Protein-Abnormal Phenotype Associations
Understanding gene functions and their associated abnormal phenotypes is crucial in the prevention, diagnosis and treatment against diseases. The Human Phenotype Ontology (HPO) is a standardized vocabulary for describing the phenotype abnormalities associated with human diseases. However, the curren...
Autores principales: | Liu, Yuan, He, Ruirui, Qu, Yingjie, Zhu, Yuan, Li, Dianke, Ling, Xinping, Xia, Simin, Li, Zhenqiu, Li, Dong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406402/ https://www.ncbi.nlm.nih.gov/pubmed/36010562 http://dx.doi.org/10.3390/cells11162485 |
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