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The Ubiquitin Ligase RNF138 Cooperates with CtIP to Stimulate Resection of Complex DNA Double-Strand Breaks in Human G1-Phase Cells

DNA double-strand breaks (DSBs) represent the molecular origin of ionizing-radiation inflicted biological effects. An increase in the ionization density causes more complex, clustered DSBs that can be processed by resection also in G1 phase, where repair of resected DSBs is considered erroneous and...

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Detalles Bibliográficos
Autores principales:	Averbeck, Nicole B., Barent, Carina, Jakob, Burkhard, Syzonenko, Tatyana, Durante, Marco, Taucher-Scholz, Gisela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406464/ https://www.ncbi.nlm.nih.gov/pubmed/36010636 http://dx.doi.org/10.3390/cells11162561

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