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The Critical Role of Hypoxia in the Re-Differentiation of Human Articular Chondrocytes
The preservation of the chondrogenic phenotype and hypoxia-related physiological microenvironment are major challenges in the 2D culture of primary human chondrocytes. To address this problem, we develop a 3D culture system generating scaffold-free spheroids from human chondrocytes. Our results high...
Autores principales: | Martinez-Armenta, Carlos, Suarez-Ahedo, Carlos, Olivos-Meza, Anell, Camacho-Rea, María C., Martínez-Gómez, Laura E., Jimenez-Gutierrez, Guadalupe Elizabeth, Martínez-Nava, Gabriela A., Gomez-Quiroz, Luis E., Pineda, Carlos, López-Reyes, Alberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406483/ https://www.ncbi.nlm.nih.gov/pubmed/36010629 http://dx.doi.org/10.3390/cells11162553 |
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