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Cognitive Decline and BPSD Are Concomitant with Autophagic and Synaptic Deficits Associated with G9a Alterations in Aged SAMP8 Mice

Behavioural and psychological symptoms of dementia (BPSD) are presented in 95% of Alzheimer’s Disease (AD) patients and are also associated with neurotrophin deficits. The molecular mechanisms leading to age-related diseases are still unclear; however, emerging evidence has suggested that epigenetic...

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Detalles Bibliográficos
Autores principales: Vasilopoulou, Foteini, Bellver-Sanchis, Aina, Companys-Alemany, Júlia, Jarne-Ferrer, Júlia, Irisarri, Alba, Palomera-Ávalos, Verónica, Gonzalez-Castillo, Celia, Ortuño-Sahagún, Daniel, Sanfeliu, Coral, Pallàs, Mercè, Griñán-Ferré, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406492/
https://www.ncbi.nlm.nih.gov/pubmed/36010679
http://dx.doi.org/10.3390/cells11162603

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