Cargando…

The Extracellular Matrix: A Key Accomplice of Cancer Stem Cell Migration, Metastasis Formation, and Drug Resistance in PDAC

SIMPLE SUMMARY: This review takes the extracellular matrix (ECM) as the starting point, and describes its influence and related mechanisms on the biological behavior of pancreatic ductal carcinoma (PDAC). It focuses on how the ECM regulates cancer stem cells and thus affects the metastasis and drug...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Dan, Li, Yuqiang, Ge, Heming, Ghadban, Tarik, Reeh, Matthias, Güngör, Cenap
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406497/ https://www.ncbi.nlm.nih.gov/pubmed/36010993 http://dx.doi.org/10.3390/cancers14163998

Ejemplares similares

Cytoskeletal and Cytoskeleton-Associated Proteins: Key Regulators of Cancer Stem Cell Properties
por: Li, Yuqiang, et al.
Publicado: (2022)

The Extracellular Matrix: An Accomplice in Gastric Cancer Development and Progression
por: Moreira, Ana Margarida, et al.
Publicado: (2020)

Survival effects of primary and metastatic surgical treatment in metastatic small intestinal tumors: A propensity score–matching study
por: Zhou, Zhongyi, et al.
Publicado: (2022)

Prognostic factors and individualized nomograms predicting overall survival in stage IV rectal cancer patients with different metastatic status: a SEER-based study
por: Ge, Heming, et al.
Publicado: (2022)

KDM5 family of demethylases promotes CD44-mediated chemoresistance in pancreatic adenocarcinomas
por: Wang, Dan, et al.
Publicado: (2023)

Neutrophil Extracellular Traps in Digestive Cancers: Warrior or Accomplice
por: Chen, Yuxin, et al.
Publicado: (2021)

SIRT 1 Overexpression is Associated with Metastasis of Pancreatic Ductal Adenocarcinoma (PDAC) and Promotes Migration and Growth of PDAC Cells
por: Li, Siqin, et al.
Publicado: (2016)

Tumors' accomplices in invasion
por: Sedwick, Caitlin
Publicado: (2007)

The covert symphony: cellular and molecular accomplices in breast cancer metastasis
por: Si, Hongjiang, et al.
Publicado: (2023)

The Role of Tumor Microenvironment in Chemoresistance: 3D Extracellular Matrices as Accomplices
por: Senthebane, Dimakatso Alice, et al.
Publicado: (2018)

Slug and E-Cadherin: Stealth Accomplices?
por: Sterneck, Esta, et al.
Publicado: (2020)

HLA‐C: An Accomplice in Rheumatic Diseases
por: Siegel, Ruby J., et al.
Publicado: (2019)

Excessive intake of sugar: An accomplice of inflammation
por: Ma, Xiao, et al.
Publicado: (2022)

EZH2: An Accomplice of Gastric Cancer
por: Yu, Wuhan, et al.
Publicado: (2023)

The Survival Effect of Radiotherapy on Stage IIB/III Pancreatic Cancer Undergone Surgery in Different Age and Tumor Site Groups: A Propensity Scores Matching Analysis Based on SEER Database
por: Wang, Dan, et al.
Publicado: (2022)

The PDAC Extracellular Matrix: A Review of the ECM Protein Composition, Tumor Cell Interaction, and Therapeutic Strategies
por: Perez, Vincent M., et al.
Publicado: (2021)

Serum midkine as non-invasive biomarker for detection and prognosis of non-small cell lung cancer
por: Stern, Louisa, et al.
Publicado: (2021)

RBFOX2: a key factor in suppressing PDAC metastasis through regulation of alternative splicing events
por: Urbach, Laura, et al.
Publicado: (2023)

PA28γ, an Accomplice to Malignant Cancer
por: Lei, Kexin, et al.
Publicado: (2020)

Autophagy, an accomplice or antagonist of drug resistance in HCC?
por: Wu, Yafei, et al.
Publicado: (2021)

Potential role of the bitter taste receptor T2R14 in the prolonged survival and enhanced chemoresponsiveness induced by apigenin
por: Stern, Louisa, et al.
Publicado: (2022)

Cancer-Associated Fibroblasts: Accomplices in the Tumor Immune Evasion
por: Hilmi, Marc, et al.
Publicado: (2020)

Unwitting Accomplices: Endocrine Disruptors Confounding Clinical Care
por: Genco, Matthew, et al.
Publicado: (2020)

Tumor-associated macrophages: an accomplice in solid tumor progression
por: Chen, Yibing, et al.
Publicado: (2019)

Syphilis and Its Accomplices in Mischief: Society, the State and the Physician
Publicado: (1941)

Malassezia in Inflammatory Bowel Disease: Accomplice of Evoking Tumorigenesis
por: Yang, Qiyu, et al.
Publicado: (2022)

Sustaining Personal Activism: Behavior Analysts as Antiracist Accomplices
por: Machalicek, Wendy, et al.
Publicado: (2021)

Tumor accomplice: T cell exhaustion induced by chronic inflammation
por: Fang, Liguang, et al.
Publicado: (2022)

Senescent Stromal Cells in the Tumor Microenvironment: Victims or Accomplices?
por: Ye, Minghan, et al.
Publicado: (2023)

Stromal cells in the tumor microenvironment: accomplices of tumor progression?
por: Zhao, Yan, et al.
Publicado: (2023)

Role of astrocytes in sleep deprivation: accomplices, resisters, or bystanders?
por: Que, Mengxin, et al.
Publicado: (2023)

Follistatin-Like 3 Enhances Invasion and Metastasis via β-Catenin-Mediated EMT and Aerobic Glycolysis in Colorectal Cancer
por: Li, Yuqiang, et al.
Publicado: (2021)

RAI3 expression is not associated with clinical outcomes of patients with non-small cell lung cancer
por: Melling, Nathaniel, et al.
Publicado: (2023)

Tumor-associated macrophages: unwitting accomplices in breast cancer malignancy
por: Williams, Carly Bess, et al.
Publicado: (2016)

Are Kynurenines Accomplices or Principal Villains in Dementia? Maintenance of Kynurenine Metabolism
por: Tanaka, Masaru, et al.
Publicado: (2020)

Cancer-associated fibroblasts as accomplices to confer therapeutic resistance in cancer
por: Wang, Wenyu, et al.
Publicado: (2022)

Extracellular Matrix Stiffness: New Areas Affecting Cell Metabolism
por: Ge, Heming, et al.
Publicado: (2021)

Identification of DDX31 as a Potential Oncogene of Invasive Metastasis and Proliferation in PDAC
por: Xie, Yongjie, et al.
Publicado: (2022)

Extracellular matrix density regulates the formation of tumour spheroids through cell migration
por: Gonçalves, Inês G., et al.
Publicado: (2021)

Bending out and breaking away: host-cell accomplices in retroviral escape
por: Yap, Melvyn W, et al.
Publicado: (2004)

Cannot write session to /tmp/vufind_sessions/sess_fnb0ia7gr134td59fad1vmb970