USP29 Deubiquitinates SETD8 and Regulates DNA Damage-Induced H4K20 Monomethylation and 53BP1 Focus Formation

SETD8 is a histone methyltransferase that plays pivotal roles in several cellular functions, including transcriptional regulation, cell cycle progression, and genome maintenance. SETD8 regulates the recruitment of 53BP1 to sites of DNA damage by controlling histone H4K20 methylation. Moreover, SETD8...

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Detalles Bibliográficos
Autores principales: Hernández-Reyes, Yeray, Paz-Cabrera, María Cristina, Freire, Raimundo, Smits, Veronique A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406528/
https://www.ncbi.nlm.nih.gov/pubmed/36010569
http://dx.doi.org/10.3390/cells11162492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406528/
https://www.ncbi.nlm.nih.gov/pubmed/36010569
http://dx.doi.org/10.3390/cells11162492

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