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USP29 Deubiquitinates SETD8 and Regulates DNA Damage-Induced H4K20 Monomethylation and 53BP1 Focus Formation
SETD8 is a histone methyltransferase that plays pivotal roles in several cellular functions, including transcriptional regulation, cell cycle progression, and genome maintenance. SETD8 regulates the recruitment of 53BP1 to sites of DNA damage by controlling histone H4K20 methylation. Moreover, SETD8...
Autores principales: | Hernández-Reyes, Yeray, Paz-Cabrera, María Cristina, Freire, Raimundo, Smits, Veronique A. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406528/ https://www.ncbi.nlm.nih.gov/pubmed/36010569 http://dx.doi.org/10.3390/cells11162492 |
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