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Functional and Survival Outcomes of Patients following the Harrington Procedure for Complex Acetabular Metastatic Lesions

Background: The Harrington surgical technique makes it possible to manage complex, extensive bone lesions using pins and cement to consolidate bone for acetabular cup positioning. However, it may be associated with a high reoperation rate, and the functional results of this surgery are not precisely...

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Autores principales: Plaud, Andrea, Gaillard, Jean, Gouin, François, Le Thuaut, Aurélie, Ageneau, Peggy, Berchoud, Juliane, Fouasson-Chailloux, Alban, Crenn, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406529/
https://www.ncbi.nlm.nih.gov/pubmed/36005202
http://dx.doi.org/10.3390/curroncol29080464
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author Plaud, Andrea
Gaillard, Jean
Gouin, François
Le Thuaut, Aurélie
Ageneau, Peggy
Berchoud, Juliane
Fouasson-Chailloux, Alban
Crenn, Vincent
author_facet Plaud, Andrea
Gaillard, Jean
Gouin, François
Le Thuaut, Aurélie
Ageneau, Peggy
Berchoud, Juliane
Fouasson-Chailloux, Alban
Crenn, Vincent
author_sort Plaud, Andrea
collection PubMed
description Background: The Harrington surgical technique makes it possible to manage complex, extensive bone lesions using pins and cement to consolidate bone for acetabular cup positioning. However, it may be associated with a high reoperation rate, and the functional results of this surgery are not precisely described in the literature. Methods: In a monocentric retrospective study including all patients operated on using the Harrington procedure associated with THA between 2005 and 2020, we aimed to assess preoperative and postoperative function, reoperation-free survival, and overall survival. Results: Functional improvement was significant for Parker scores (preoperative: 3.6 ± 2.0; 6-month follow-up: 6.6 ± 3.2; 12-month follow-up: 7.6 ± 2.1) and Musculoskeletal Tumor Society (MSTS) scores (preoperative: 31.1 ± 16.2%; 6-month follow-up: 67.7 ± 30.6%; 12-month follow-up: 82.4 ± 24.0%). Of the 21 patients included, the reoperation-free survival rate was 76.1% [CI 95%: 58.1–99.7] at six and twelve months, with the main complications being pin migration (50.0%) and infection (25%). The patient overall survival rate was 76.2% [95% CI: 59.9–96.7] at six months and 61.9% [95% CI: 59.9–96.7] at 12 months. Discussion: These results underlined significant functional improvements following a conventional Harrington procedure, with acceptable reoperation rates.
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spelling pubmed-94065292022-08-26 Functional and Survival Outcomes of Patients following the Harrington Procedure for Complex Acetabular Metastatic Lesions Plaud, Andrea Gaillard, Jean Gouin, François Le Thuaut, Aurélie Ageneau, Peggy Berchoud, Juliane Fouasson-Chailloux, Alban Crenn, Vincent Curr Oncol Article Background: The Harrington surgical technique makes it possible to manage complex, extensive bone lesions using pins and cement to consolidate bone for acetabular cup positioning. However, it may be associated with a high reoperation rate, and the functional results of this surgery are not precisely described in the literature. Methods: In a monocentric retrospective study including all patients operated on using the Harrington procedure associated with THA between 2005 and 2020, we aimed to assess preoperative and postoperative function, reoperation-free survival, and overall survival. Results: Functional improvement was significant for Parker scores (preoperative: 3.6 ± 2.0; 6-month follow-up: 6.6 ± 3.2; 12-month follow-up: 7.6 ± 2.1) and Musculoskeletal Tumor Society (MSTS) scores (preoperative: 31.1 ± 16.2%; 6-month follow-up: 67.7 ± 30.6%; 12-month follow-up: 82.4 ± 24.0%). Of the 21 patients included, the reoperation-free survival rate was 76.1% [CI 95%: 58.1–99.7] at six and twelve months, with the main complications being pin migration (50.0%) and infection (25%). The patient overall survival rate was 76.2% [95% CI: 59.9–96.7] at six months and 61.9% [95% CI: 59.9–96.7] at 12 months. Discussion: These results underlined significant functional improvements following a conventional Harrington procedure, with acceptable reoperation rates. MDPI 2022-08-19 /pmc/articles/PMC9406529/ /pubmed/36005202 http://dx.doi.org/10.3390/curroncol29080464 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Plaud, Andrea
Gaillard, Jean
Gouin, François
Le Thuaut, Aurélie
Ageneau, Peggy
Berchoud, Juliane
Fouasson-Chailloux, Alban
Crenn, Vincent
Functional and Survival Outcomes of Patients following the Harrington Procedure for Complex Acetabular Metastatic Lesions
title Functional and Survival Outcomes of Patients following the Harrington Procedure for Complex Acetabular Metastatic Lesions
title_full Functional and Survival Outcomes of Patients following the Harrington Procedure for Complex Acetabular Metastatic Lesions
title_fullStr Functional and Survival Outcomes of Patients following the Harrington Procedure for Complex Acetabular Metastatic Lesions
title_full_unstemmed Functional and Survival Outcomes of Patients following the Harrington Procedure for Complex Acetabular Metastatic Lesions
title_short Functional and Survival Outcomes of Patients following the Harrington Procedure for Complex Acetabular Metastatic Lesions
title_sort functional and survival outcomes of patients following the harrington procedure for complex acetabular metastatic lesions
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406529/
https://www.ncbi.nlm.nih.gov/pubmed/36005202
http://dx.doi.org/10.3390/curroncol29080464
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