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p73α1, an Isoform of the p73 Tumor Suppressor, Modulates Lipid Metabolism and Cancer Cell Growth via Stearoyl-CoA Desaturase-1

Altered lipid metabolism is a hallmark of cancer. p73, a p53 family member, regulates cellular processes and is expressed as multiple isoforms. However, the role of p73 in regulating lipid metabolism is not well-characterized. Previously, we found that loss of p73 exon 12 (E12) leads to an isoform s...

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Detalles Bibliográficos
Autores principales: Rabow, Zachary, Laubach, Kyra, Kong, Xiangmudong, Shen, Tong, Mohibi, Shakur, Zhang, Jin, Fiehn, Oliver, Chen, Xinbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406568/
https://www.ncbi.nlm.nih.gov/pubmed/36010592
http://dx.doi.org/10.3390/cells11162516

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