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Pediatric Tuberculosis Management: A Global Challenge or Breakthrough?

Managing pediatric tuberculosis (TB) remains a public health problem requiring urgent and long-lasting solutions as TB is one of the top ten causes of ill health and death in children as well as adolescents universally. Minors are particularly susceptible to this severe illness that can be fatal pos...

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Autores principales: Maphalle, Lehlogonolo N. F., Michniak-Kohn, Bozena B., Ogunrombi, Modupe O., Adeleke, Oluwatoyin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406656/
https://www.ncbi.nlm.nih.gov/pubmed/36010011
http://dx.doi.org/10.3390/children9081120
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author Maphalle, Lehlogonolo N. F.
Michniak-Kohn, Bozena B.
Ogunrombi, Modupe O.
Adeleke, Oluwatoyin A.
author_facet Maphalle, Lehlogonolo N. F.
Michniak-Kohn, Bozena B.
Ogunrombi, Modupe O.
Adeleke, Oluwatoyin A.
author_sort Maphalle, Lehlogonolo N. F.
collection PubMed
description Managing pediatric tuberculosis (TB) remains a public health problem requiring urgent and long-lasting solutions as TB is one of the top ten causes of ill health and death in children as well as adolescents universally. Minors are particularly susceptible to this severe illness that can be fatal post-infection or even serve as reservoirs for future disease outbreaks. However, pediatric TB is the least prioritized in most health programs and optimal infection/disease control has been quite neglected for this specialized patient category, as most scientific and clinical research efforts focus on developing novel management strategies for adults. Moreover, the ongoing coronavirus pandemic has meaningfully hindered the gains and progress achieved with TB prophylaxis, therapy, diagnosis, and global eradication goals for all affected persons of varying age bands. Thus, the opening of novel research activities and opportunities that can provide more insight and create new knowledge specifically geared towards managing TB disease in this specialized group will significantly improve their well-being and longevity.
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spelling pubmed-94066562022-08-26 Pediatric Tuberculosis Management: A Global Challenge or Breakthrough? Maphalle, Lehlogonolo N. F. Michniak-Kohn, Bozena B. Ogunrombi, Modupe O. Adeleke, Oluwatoyin A. Children (Basel) Review Managing pediatric tuberculosis (TB) remains a public health problem requiring urgent and long-lasting solutions as TB is one of the top ten causes of ill health and death in children as well as adolescents universally. Minors are particularly susceptible to this severe illness that can be fatal post-infection or even serve as reservoirs for future disease outbreaks. However, pediatric TB is the least prioritized in most health programs and optimal infection/disease control has been quite neglected for this specialized patient category, as most scientific and clinical research efforts focus on developing novel management strategies for adults. Moreover, the ongoing coronavirus pandemic has meaningfully hindered the gains and progress achieved with TB prophylaxis, therapy, diagnosis, and global eradication goals for all affected persons of varying age bands. Thus, the opening of novel research activities and opportunities that can provide more insight and create new knowledge specifically geared towards managing TB disease in this specialized group will significantly improve their well-being and longevity. MDPI 2022-07-27 /pmc/articles/PMC9406656/ /pubmed/36010011 http://dx.doi.org/10.3390/children9081120 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Maphalle, Lehlogonolo N. F.
Michniak-Kohn, Bozena B.
Ogunrombi, Modupe O.
Adeleke, Oluwatoyin A.
Pediatric Tuberculosis Management: A Global Challenge or Breakthrough?
title Pediatric Tuberculosis Management: A Global Challenge or Breakthrough?
title_full Pediatric Tuberculosis Management: A Global Challenge or Breakthrough?
title_fullStr Pediatric Tuberculosis Management: A Global Challenge or Breakthrough?
title_full_unstemmed Pediatric Tuberculosis Management: A Global Challenge or Breakthrough?
title_short Pediatric Tuberculosis Management: A Global Challenge or Breakthrough?
title_sort pediatric tuberculosis management: a global challenge or breakthrough?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406656/
https://www.ncbi.nlm.nih.gov/pubmed/36010011
http://dx.doi.org/10.3390/children9081120
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