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Lowering of the Neonatal Lung Ultrasonography Score after nCPAP Positioning in Neonates over 32 Weeks of Gestational Age with Neonatal Respiratory Distress
Respiratory distress (RD) is one of the most common causes of admission to the neonatal intensive care unit. Correct diagnosis and timely intervention are crucial. Lung ultrasonography (LU) is a useful diagnostic tool for the neonatologist in the diagnosis of RD; the neonatal lung ultrasonography sc...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406690/ https://www.ncbi.nlm.nih.gov/pubmed/36010259 http://dx.doi.org/10.3390/diagnostics12081909 |
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author | Perri, Alessandro Fattore, Simona D’Andrea, Vito Sbordone, Annamaria Patti, Maria Letizia Nobile, Stefano Tirone, Chiara Giordano, Lucia Tana, Milena Priolo, Francesca Serrao, Francesca Riccardi, Riccardo Prontera, Giorgia Vento, Giovanni |
author_facet | Perri, Alessandro Fattore, Simona D’Andrea, Vito Sbordone, Annamaria Patti, Maria Letizia Nobile, Stefano Tirone, Chiara Giordano, Lucia Tana, Milena Priolo, Francesca Serrao, Francesca Riccardi, Riccardo Prontera, Giorgia Vento, Giovanni |
author_sort | Perri, Alessandro |
collection | PubMed |
description | Respiratory distress (RD) is one of the most common causes of admission to the neonatal intensive care unit. Correct diagnosis and timely intervention are crucial. Lung ultrasonography (LU) is a useful diagnostic tool for the neonatologist in the diagnosis of RD; the neonatal lung ultrasonography score (nLUS) can be used in the diagnostic process, but some authors hypothesise that it is also useful for the management of some neonatal RD. The aim of this study is to analyse the changes in nLUS score before (T0) and after (T1) the start of respiratory support with nasal CPAP in neonates over 32 weeks of age with RD. Thirty-three newborns were enrolled in this retrospective study. LU was performed before and after the start of CPAP. The median nLUS scores at T0 and T1 were 9 (IQR 7–12) and 7 (IQR 4–10), respectively, and showed a significant difference (p < 0.001). The magnitude of reduction in nLUS score, expressed as a percentage, was inversely related to the need for subsequent administration of exogenous surfactant. The study suggests the usefulness of the nLUS score in assessing the response to CPAP in neonates over 32 weeks gestational age. |
format | Online Article Text |
id | pubmed-9406690 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-94066902022-08-26 Lowering of the Neonatal Lung Ultrasonography Score after nCPAP Positioning in Neonates over 32 Weeks of Gestational Age with Neonatal Respiratory Distress Perri, Alessandro Fattore, Simona D’Andrea, Vito Sbordone, Annamaria Patti, Maria Letizia Nobile, Stefano Tirone, Chiara Giordano, Lucia Tana, Milena Priolo, Francesca Serrao, Francesca Riccardi, Riccardo Prontera, Giorgia Vento, Giovanni Diagnostics (Basel) Article Respiratory distress (RD) is one of the most common causes of admission to the neonatal intensive care unit. Correct diagnosis and timely intervention are crucial. Lung ultrasonography (LU) is a useful diagnostic tool for the neonatologist in the diagnosis of RD; the neonatal lung ultrasonography score (nLUS) can be used in the diagnostic process, but some authors hypothesise that it is also useful for the management of some neonatal RD. The aim of this study is to analyse the changes in nLUS score before (T0) and after (T1) the start of respiratory support with nasal CPAP in neonates over 32 weeks of age with RD. Thirty-three newborns were enrolled in this retrospective study. LU was performed before and after the start of CPAP. The median nLUS scores at T0 and T1 were 9 (IQR 7–12) and 7 (IQR 4–10), respectively, and showed a significant difference (p < 0.001). The magnitude of reduction in nLUS score, expressed as a percentage, was inversely related to the need for subsequent administration of exogenous surfactant. The study suggests the usefulness of the nLUS score in assessing the response to CPAP in neonates over 32 weeks gestational age. MDPI 2022-08-07 /pmc/articles/PMC9406690/ /pubmed/36010259 http://dx.doi.org/10.3390/diagnostics12081909 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Perri, Alessandro Fattore, Simona D’Andrea, Vito Sbordone, Annamaria Patti, Maria Letizia Nobile, Stefano Tirone, Chiara Giordano, Lucia Tana, Milena Priolo, Francesca Serrao, Francesca Riccardi, Riccardo Prontera, Giorgia Vento, Giovanni Lowering of the Neonatal Lung Ultrasonography Score after nCPAP Positioning in Neonates over 32 Weeks of Gestational Age with Neonatal Respiratory Distress |
title | Lowering of the Neonatal Lung Ultrasonography Score after nCPAP Positioning in Neonates over 32 Weeks of Gestational Age with Neonatal Respiratory Distress |
title_full | Lowering of the Neonatal Lung Ultrasonography Score after nCPAP Positioning in Neonates over 32 Weeks of Gestational Age with Neonatal Respiratory Distress |
title_fullStr | Lowering of the Neonatal Lung Ultrasonography Score after nCPAP Positioning in Neonates over 32 Weeks of Gestational Age with Neonatal Respiratory Distress |
title_full_unstemmed | Lowering of the Neonatal Lung Ultrasonography Score after nCPAP Positioning in Neonates over 32 Weeks of Gestational Age with Neonatal Respiratory Distress |
title_short | Lowering of the Neonatal Lung Ultrasonography Score after nCPAP Positioning in Neonates over 32 Weeks of Gestational Age with Neonatal Respiratory Distress |
title_sort | lowering of the neonatal lung ultrasonography score after ncpap positioning in neonates over 32 weeks of gestational age with neonatal respiratory distress |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406690/ https://www.ncbi.nlm.nih.gov/pubmed/36010259 http://dx.doi.org/10.3390/diagnostics12081909 |
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