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Lowering of the Neonatal Lung Ultrasonography Score after nCPAP Positioning in Neonates over 32 Weeks of Gestational Age with Neonatal Respiratory Distress

Respiratory distress (RD) is one of the most common causes of admission to the neonatal intensive care unit. Correct diagnosis and timely intervention are crucial. Lung ultrasonography (LU) is a useful diagnostic tool for the neonatologist in the diagnosis of RD; the neonatal lung ultrasonography sc...

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Autores principales: Perri, Alessandro, Fattore, Simona, D’Andrea, Vito, Sbordone, Annamaria, Patti, Maria Letizia, Nobile, Stefano, Tirone, Chiara, Giordano, Lucia, Tana, Milena, Priolo, Francesca, Serrao, Francesca, Riccardi, Riccardo, Prontera, Giorgia, Vento, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406690/
https://www.ncbi.nlm.nih.gov/pubmed/36010259
http://dx.doi.org/10.3390/diagnostics12081909
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author Perri, Alessandro
Fattore, Simona
D’Andrea, Vito
Sbordone, Annamaria
Patti, Maria Letizia
Nobile, Stefano
Tirone, Chiara
Giordano, Lucia
Tana, Milena
Priolo, Francesca
Serrao, Francesca
Riccardi, Riccardo
Prontera, Giorgia
Vento, Giovanni
author_facet Perri, Alessandro
Fattore, Simona
D’Andrea, Vito
Sbordone, Annamaria
Patti, Maria Letizia
Nobile, Stefano
Tirone, Chiara
Giordano, Lucia
Tana, Milena
Priolo, Francesca
Serrao, Francesca
Riccardi, Riccardo
Prontera, Giorgia
Vento, Giovanni
author_sort Perri, Alessandro
collection PubMed
description Respiratory distress (RD) is one of the most common causes of admission to the neonatal intensive care unit. Correct diagnosis and timely intervention are crucial. Lung ultrasonography (LU) is a useful diagnostic tool for the neonatologist in the diagnosis of RD; the neonatal lung ultrasonography score (nLUS) can be used in the diagnostic process, but some authors hypothesise that it is also useful for the management of some neonatal RD. The aim of this study is to analyse the changes in nLUS score before (T0) and after (T1) the start of respiratory support with nasal CPAP in neonates over 32 weeks of age with RD. Thirty-three newborns were enrolled in this retrospective study. LU was performed before and after the start of CPAP. The median nLUS scores at T0 and T1 were 9 (IQR 7–12) and 7 (IQR 4–10), respectively, and showed a significant difference (p < 0.001). The magnitude of reduction in nLUS score, expressed as a percentage, was inversely related to the need for subsequent administration of exogenous surfactant. The study suggests the usefulness of the nLUS score in assessing the response to CPAP in neonates over 32 weeks gestational age.
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spelling pubmed-94066902022-08-26 Lowering of the Neonatal Lung Ultrasonography Score after nCPAP Positioning in Neonates over 32 Weeks of Gestational Age with Neonatal Respiratory Distress Perri, Alessandro Fattore, Simona D’Andrea, Vito Sbordone, Annamaria Patti, Maria Letizia Nobile, Stefano Tirone, Chiara Giordano, Lucia Tana, Milena Priolo, Francesca Serrao, Francesca Riccardi, Riccardo Prontera, Giorgia Vento, Giovanni Diagnostics (Basel) Article Respiratory distress (RD) is one of the most common causes of admission to the neonatal intensive care unit. Correct diagnosis and timely intervention are crucial. Lung ultrasonography (LU) is a useful diagnostic tool for the neonatologist in the diagnosis of RD; the neonatal lung ultrasonography score (nLUS) can be used in the diagnostic process, but some authors hypothesise that it is also useful for the management of some neonatal RD. The aim of this study is to analyse the changes in nLUS score before (T0) and after (T1) the start of respiratory support with nasal CPAP in neonates over 32 weeks of age with RD. Thirty-three newborns were enrolled in this retrospective study. LU was performed before and after the start of CPAP. The median nLUS scores at T0 and T1 were 9 (IQR 7–12) and 7 (IQR 4–10), respectively, and showed a significant difference (p < 0.001). The magnitude of reduction in nLUS score, expressed as a percentage, was inversely related to the need for subsequent administration of exogenous surfactant. The study suggests the usefulness of the nLUS score in assessing the response to CPAP in neonates over 32 weeks gestational age. MDPI 2022-08-07 /pmc/articles/PMC9406690/ /pubmed/36010259 http://dx.doi.org/10.3390/diagnostics12081909 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Perri, Alessandro
Fattore, Simona
D’Andrea, Vito
Sbordone, Annamaria
Patti, Maria Letizia
Nobile, Stefano
Tirone, Chiara
Giordano, Lucia
Tana, Milena
Priolo, Francesca
Serrao, Francesca
Riccardi, Riccardo
Prontera, Giorgia
Vento, Giovanni
Lowering of the Neonatal Lung Ultrasonography Score after nCPAP Positioning in Neonates over 32 Weeks of Gestational Age with Neonatal Respiratory Distress
title Lowering of the Neonatal Lung Ultrasonography Score after nCPAP Positioning in Neonates over 32 Weeks of Gestational Age with Neonatal Respiratory Distress
title_full Lowering of the Neonatal Lung Ultrasonography Score after nCPAP Positioning in Neonates over 32 Weeks of Gestational Age with Neonatal Respiratory Distress
title_fullStr Lowering of the Neonatal Lung Ultrasonography Score after nCPAP Positioning in Neonates over 32 Weeks of Gestational Age with Neonatal Respiratory Distress
title_full_unstemmed Lowering of the Neonatal Lung Ultrasonography Score after nCPAP Positioning in Neonates over 32 Weeks of Gestational Age with Neonatal Respiratory Distress
title_short Lowering of the Neonatal Lung Ultrasonography Score after nCPAP Positioning in Neonates over 32 Weeks of Gestational Age with Neonatal Respiratory Distress
title_sort lowering of the neonatal lung ultrasonography score after ncpap positioning in neonates over 32 weeks of gestational age with neonatal respiratory distress
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406690/
https://www.ncbi.nlm.nih.gov/pubmed/36010259
http://dx.doi.org/10.3390/diagnostics12081909
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