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Neonatal Platelets: Lower G(12/13) Expression Contributes to Reduced Secretion of Dense Granules

Despite fully functional primary hemostasis, platelets of healthy neonates exhibit hypoaggregability and secretion defects, which may be adaptations to specific requirements in this developmental stage. The etiologies for reduced signal transduction vary with the type of agonist. The discovered pecu...

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Detalles Bibliográficos
Autores principales: Schlagenhauf, Axel, Bohler, Sheila, Kunze, Mirjam, Strini, Tanja, Haidl, Harald, Erlacher, Miriam, Zieger, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406762/
https://www.ncbi.nlm.nih.gov/pubmed/36010639
http://dx.doi.org/10.3390/cells11162563