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Reproducibility and Reliability of Spectralis II OCT Angiography Vascular Measurements

Purpose: to investigate the reproducibility and reliability of OCT-A vascular measurements using Heidelberg Spectralis II OCT-A. Methods: a prospective study involving a single eye of patients aged 18 or older with no ocular disease. In order to investigate the reliability of the first and second OC...

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Autores principales: Pastore, Marco R., Grotto, Alberto, Vezzoni, Francesca, Gaggino, Andrea, Milan, Serena, Gouigoux, Stefano, Guerin, Pier Luigi, Vinciguerra, Alex L., Cirigliano, Gabriella, Tognetto, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406840/
https://www.ncbi.nlm.nih.gov/pubmed/36010258
http://dx.doi.org/10.3390/diagnostics12081908
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author Pastore, Marco R.
Grotto, Alberto
Vezzoni, Francesca
Gaggino, Andrea
Milan, Serena
Gouigoux, Stefano
Guerin, Pier Luigi
Vinciguerra, Alex L.
Cirigliano, Gabriella
Tognetto, Daniele
author_facet Pastore, Marco R.
Grotto, Alberto
Vezzoni, Francesca
Gaggino, Andrea
Milan, Serena
Gouigoux, Stefano
Guerin, Pier Luigi
Vinciguerra, Alex L.
Cirigliano, Gabriella
Tognetto, Daniele
author_sort Pastore, Marco R.
collection PubMed
description Purpose: to investigate the reproducibility and reliability of OCT-A vascular measurements using Heidelberg Spectralis II OCT-A. Methods: a prospective study involving a single eye of patients aged 18 or older with no ocular disease. In order to investigate the reliability of the first and second OCT-A scans, the coefficient of variation of the foveal avascular zone (FAZ) and the vessel density (VD) in the superficial (SCP), intermediate (ICP) and deep capillary plexus (DCP) were calculated. Results: A total of 75 eyes were included in the study. The mean FAZ in the first and second scan was 0.36 × 0.13 mm(2) and 0.37 × 0.12 mm(2), respectively, in the SCP, 0.23 × 0.10 mm(2) and 0.23 × 0.09 mm(2) in the ICP, and 0.42 × 0.11 mm(2) and 0.43 × 0.12 mm(2) in the DCP. The overall VD was 36.05 × 9.01 and 35.33 × 9.92 at the first and second scan, respectively, in the SCP, 21.87 × 5.00 and 21.32 × 5.56 in the ICP, and 23.84 × 6.53 and 23.20 × 6.83 in the DCP. No statistically significant differences in FAZ measurements and VD in all sectors of each capillary plexus were observed between the first and second scan (p > 0.05). Conclusion: our study demonstrated the good reproducibility and reliability of OCT-A vascular measurements in the analysis of the FAZ and the quantification of VD in each capillary plexus of the retina.
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spelling pubmed-94068402022-08-26 Reproducibility and Reliability of Spectralis II OCT Angiography Vascular Measurements Pastore, Marco R. Grotto, Alberto Vezzoni, Francesca Gaggino, Andrea Milan, Serena Gouigoux, Stefano Guerin, Pier Luigi Vinciguerra, Alex L. Cirigliano, Gabriella Tognetto, Daniele Diagnostics (Basel) Article Purpose: to investigate the reproducibility and reliability of OCT-A vascular measurements using Heidelberg Spectralis II OCT-A. Methods: a prospective study involving a single eye of patients aged 18 or older with no ocular disease. In order to investigate the reliability of the first and second OCT-A scans, the coefficient of variation of the foveal avascular zone (FAZ) and the vessel density (VD) in the superficial (SCP), intermediate (ICP) and deep capillary plexus (DCP) were calculated. Results: A total of 75 eyes were included in the study. The mean FAZ in the first and second scan was 0.36 × 0.13 mm(2) and 0.37 × 0.12 mm(2), respectively, in the SCP, 0.23 × 0.10 mm(2) and 0.23 × 0.09 mm(2) in the ICP, and 0.42 × 0.11 mm(2) and 0.43 × 0.12 mm(2) in the DCP. The overall VD was 36.05 × 9.01 and 35.33 × 9.92 at the first and second scan, respectively, in the SCP, 21.87 × 5.00 and 21.32 × 5.56 in the ICP, and 23.84 × 6.53 and 23.20 × 6.83 in the DCP. No statistically significant differences in FAZ measurements and VD in all sectors of each capillary plexus were observed between the first and second scan (p > 0.05). Conclusion: our study demonstrated the good reproducibility and reliability of OCT-A vascular measurements in the analysis of the FAZ and the quantification of VD in each capillary plexus of the retina. MDPI 2022-08-07 /pmc/articles/PMC9406840/ /pubmed/36010258 http://dx.doi.org/10.3390/diagnostics12081908 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Pastore, Marco R.
Grotto, Alberto
Vezzoni, Francesca
Gaggino, Andrea
Milan, Serena
Gouigoux, Stefano
Guerin, Pier Luigi
Vinciguerra, Alex L.
Cirigliano, Gabriella
Tognetto, Daniele
Reproducibility and Reliability of Spectralis II OCT Angiography Vascular Measurements
title Reproducibility and Reliability of Spectralis II OCT Angiography Vascular Measurements
title_full Reproducibility and Reliability of Spectralis II OCT Angiography Vascular Measurements
title_fullStr Reproducibility and Reliability of Spectralis II OCT Angiography Vascular Measurements
title_full_unstemmed Reproducibility and Reliability of Spectralis II OCT Angiography Vascular Measurements
title_short Reproducibility and Reliability of Spectralis II OCT Angiography Vascular Measurements
title_sort reproducibility and reliability of spectralis ii oct angiography vascular measurements
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406840/
https://www.ncbi.nlm.nih.gov/pubmed/36010258
http://dx.doi.org/10.3390/diagnostics12081908
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