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Adrenal Crisis Mimicking COVID-19 Encephalopathy in a Teenager with Craniopharyngioma
There is an increasing number of reported cases with neurological manifestations of COVID-19 in children. Symptoms include headache, general malaise, ageusia, seizure and alterations in consciousness. The differential diagnosis includes several potentially lethal conditions including encephalopathy,...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406844/ https://www.ncbi.nlm.nih.gov/pubmed/36010128 http://dx.doi.org/10.3390/children9081238 |
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author | Chien, Tzu-Chien Chien, Mu-Ming Liu, Tsai-Ling Chang, Hsi Tsai, Min-Lan Tseng, Sung-Hui Ho, Wan-Ling Su, Yi-Yu Lin, Hsiu-Chen Lu, Jen-Her Chang, Chia-Yau Hsieh, Kevin Li-Chun Wong, Tai-Tong Miser, James S. Liu, Yen-Lin |
author_facet | Chien, Tzu-Chien Chien, Mu-Ming Liu, Tsai-Ling Chang, Hsi Tsai, Min-Lan Tseng, Sung-Hui Ho, Wan-Ling Su, Yi-Yu Lin, Hsiu-Chen Lu, Jen-Her Chang, Chia-Yau Hsieh, Kevin Li-Chun Wong, Tai-Tong Miser, James S. Liu, Yen-Lin |
author_sort | Chien, Tzu-Chien |
collection | PubMed |
description | There is an increasing number of reported cases with neurological manifestations of COVID-19 in children. Symptoms include headache, general malaise, ageusia, seizure and alterations in consciousness. The differential diagnosis includes several potentially lethal conditions including encephalopathy, encephalitis, intracranial hemorrhage, thrombosis and adrenal crisis. We report the case of a 17-year-old boy with a positive antigen test of COVID-19 who presented with fever for one day, altered mental status and seizure, subsequently diagnosed with adrenal insufficiency. He had a history of panhypopituitarism secondary to a suprasellar craniopharyngioma treated with surgical resection; he was treated with regular hormone replacement therapy. After prompt administration of intravenous hydrocortisone, his mental status returned to normal within four hours. He recovered without neurologic complications. Adrenal insufficiency can present with neurological manifestations mimicking COVID-19 encephalopathy. Prompt recognition and treatment of adrenal insufficiency, especially in patients with brain tumors, Addison’s disease or those recently treated with corticosteroids, can rapidly improve the clinical condition and prevent long-term consequences. |
format | Online Article Text |
id | pubmed-9406844 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-94068442022-08-26 Adrenal Crisis Mimicking COVID-19 Encephalopathy in a Teenager with Craniopharyngioma Chien, Tzu-Chien Chien, Mu-Ming Liu, Tsai-Ling Chang, Hsi Tsai, Min-Lan Tseng, Sung-Hui Ho, Wan-Ling Su, Yi-Yu Lin, Hsiu-Chen Lu, Jen-Her Chang, Chia-Yau Hsieh, Kevin Li-Chun Wong, Tai-Tong Miser, James S. Liu, Yen-Lin Children (Basel) Case Report There is an increasing number of reported cases with neurological manifestations of COVID-19 in children. Symptoms include headache, general malaise, ageusia, seizure and alterations in consciousness. The differential diagnosis includes several potentially lethal conditions including encephalopathy, encephalitis, intracranial hemorrhage, thrombosis and adrenal crisis. We report the case of a 17-year-old boy with a positive antigen test of COVID-19 who presented with fever for one day, altered mental status and seizure, subsequently diagnosed with adrenal insufficiency. He had a history of panhypopituitarism secondary to a suprasellar craniopharyngioma treated with surgical resection; he was treated with regular hormone replacement therapy. After prompt administration of intravenous hydrocortisone, his mental status returned to normal within four hours. He recovered without neurologic complications. Adrenal insufficiency can present with neurological manifestations mimicking COVID-19 encephalopathy. Prompt recognition and treatment of adrenal insufficiency, especially in patients with brain tumors, Addison’s disease or those recently treated with corticosteroids, can rapidly improve the clinical condition and prevent long-term consequences. MDPI 2022-08-17 /pmc/articles/PMC9406844/ /pubmed/36010128 http://dx.doi.org/10.3390/children9081238 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Chien, Tzu-Chien Chien, Mu-Ming Liu, Tsai-Ling Chang, Hsi Tsai, Min-Lan Tseng, Sung-Hui Ho, Wan-Ling Su, Yi-Yu Lin, Hsiu-Chen Lu, Jen-Her Chang, Chia-Yau Hsieh, Kevin Li-Chun Wong, Tai-Tong Miser, James S. Liu, Yen-Lin Adrenal Crisis Mimicking COVID-19 Encephalopathy in a Teenager with Craniopharyngioma |
title | Adrenal Crisis Mimicking COVID-19 Encephalopathy in a Teenager with Craniopharyngioma |
title_full | Adrenal Crisis Mimicking COVID-19 Encephalopathy in a Teenager with Craniopharyngioma |
title_fullStr | Adrenal Crisis Mimicking COVID-19 Encephalopathy in a Teenager with Craniopharyngioma |
title_full_unstemmed | Adrenal Crisis Mimicking COVID-19 Encephalopathy in a Teenager with Craniopharyngioma |
title_short | Adrenal Crisis Mimicking COVID-19 Encephalopathy in a Teenager with Craniopharyngioma |
title_sort | adrenal crisis mimicking covid-19 encephalopathy in a teenager with craniopharyngioma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406844/ https://www.ncbi.nlm.nih.gov/pubmed/36010128 http://dx.doi.org/10.3390/children9081238 |
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