Low Impact of Clonal Hematopoiesis on the Determination of RAS Mutations by Cell-Free DNA Testing in Routine Clinical Diagnostics

Targeted sequencing of circulating cell-free DNA (cfDNA) is used in routine clinical diagnostics for the identification of predictive biomarkers in cancer patients in an advanced stage. The presence of KRAS mutations associated with clonal hematopoiesis of indeterminate potential (CHIP) might repres...

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Detalles Bibliográficos
Autores principales: Roma, Cristin, Sacco, Alessandra, Forgione, Laura, Esposito Abate, Riziero, Lambiase, Matilde, Dotolo, Serena, Maiello, Monica Rosaria, Frezzetti, Daniela, Nasti, Guglielmo, Morabito, Alessandro, De Luca, Antonella, Normanno, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406879/
https://www.ncbi.nlm.nih.gov/pubmed/36010306
http://dx.doi.org/10.3390/diagnostics12081956

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