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Tracing the Origin of Cell-Free DNA Molecules through Tissue-Specific Epigenetic Signatures
All cell and tissue types constantly release DNA fragments into human body fluids by various mechanisms including programmed cell death, accidental cell degradation and active extrusion. Particularly, cell-free DNA (cfDNA) in plasma or serum has been utilized for minimally invasive molecular diagnos...
Autores principales: | Oberhofer, Angela, Bronkhorst, Abel J., Uhlig, Carsten, Ungerer, Vida, Holdenrieder, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406971/ https://www.ncbi.nlm.nih.gov/pubmed/36010184 http://dx.doi.org/10.3390/diagnostics12081834 |
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