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Ablation of NLRP3 inflammasome rewires MDSC function and promotes tumor regression

Myeloid-derived suppressor cells (MDSCs) are myeloid precursors that exert potent immunosuppressive properties in cancer. Despite the extensive knowledge on mechanisms implicated in mobilization, recruitment, and function of MDSCs, their therapeutic targeting remains an unmet need in cancer immunoth...

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Detalles Bibliográficos
Autores principales:	Papafragkos, Iosif, Grigoriou, Maria, Boon, Louis, Kloetgen, Andreas, Hatzioannou, Aikaterini, Verginis, Panayotis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407017/ https://www.ncbi.nlm.nih.gov/pubmed/36032139 http://dx.doi.org/10.3389/fimmu.2022.889075

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