Cargando…

Custom 3D fMRI Registration Template Construction Method Based on Time-Series Fusion

As the brain standard template for medical image registration has only been constructed with an MRI template, there is no three-dimensional fMRI standard template for use, and when the subject’s brain structure is quite different from the standard brain structure, the registration to the standard sp...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Zhongyang, Xin, Junchang, Shen, Huixian, Chen, Qi, Wang, Zhiqiong, Wang, Xinlei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407088/
https://www.ncbi.nlm.nih.gov/pubmed/36010363
http://dx.doi.org/10.3390/diagnostics12082013
_version_ 1784774279032733696
author Wang, Zhongyang
Xin, Junchang
Shen, Huixian
Chen, Qi
Wang, Zhiqiong
Wang, Xinlei
author_facet Wang, Zhongyang
Xin, Junchang
Shen, Huixian
Chen, Qi
Wang, Zhiqiong
Wang, Xinlei
author_sort Wang, Zhongyang
collection PubMed
description As the brain standard template for medical image registration has only been constructed with an MRI template, there is no three-dimensional fMRI standard template for use, and when the subject’s brain structure is quite different from the standard brain structure, the registration to the standard space will lead to large errors. Registration to an individual space can avoid this problem. However, in the current fMRI registration algorithm based on individual space, the reference image is often selected by researchers or randomly selected fMRI images at a certain time point. This makes the quality of the reference image very dependent on the experience and ability of the researchers and has great contingency. Whether the reference image is appropriate and reasonable affects the rationality and accuracy of the registration results to a great extent. Therefore, a method for constructing a 3D custom fMRI template is proposed. First, the data are preprocessed; second, by taking a group of two-dimensional slices corresponding to the same layer of the brain in three-dimensional fMRI images at multiple time points as image sequences, each group of slice sequences are registered and fused; and finally, a group of fused slices corresponding to different layers of the brain are obtained. In the process of registration, in order to make full use of the correlation information between the sequence data, the feature points of each two slices of adjacent time points in the sequence are matched, and then according to the transformation relationship between the adjacent images, they are recursively forwarded and mapped to the same space. Then, the fused slices are stacked in order to form a three-dimensional customized fMRI template with individual pertinence. Finally, in the classic registration algorithm, the difference in the registration accuracy between using a custom fMRI template and different standard spaces is compared, which proves that using a custom template can improve the registration effect to a certain extent.
format Online
Article
Text
id pubmed-9407088
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-94070882022-08-26 Custom 3D fMRI Registration Template Construction Method Based on Time-Series Fusion Wang, Zhongyang Xin, Junchang Shen, Huixian Chen, Qi Wang, Zhiqiong Wang, Xinlei Diagnostics (Basel) Article As the brain standard template for medical image registration has only been constructed with an MRI template, there is no three-dimensional fMRI standard template for use, and when the subject’s brain structure is quite different from the standard brain structure, the registration to the standard space will lead to large errors. Registration to an individual space can avoid this problem. However, in the current fMRI registration algorithm based on individual space, the reference image is often selected by researchers or randomly selected fMRI images at a certain time point. This makes the quality of the reference image very dependent on the experience and ability of the researchers and has great contingency. Whether the reference image is appropriate and reasonable affects the rationality and accuracy of the registration results to a great extent. Therefore, a method for constructing a 3D custom fMRI template is proposed. First, the data are preprocessed; second, by taking a group of two-dimensional slices corresponding to the same layer of the brain in three-dimensional fMRI images at multiple time points as image sequences, each group of slice sequences are registered and fused; and finally, a group of fused slices corresponding to different layers of the brain are obtained. In the process of registration, in order to make full use of the correlation information between the sequence data, the feature points of each two slices of adjacent time points in the sequence are matched, and then according to the transformation relationship between the adjacent images, they are recursively forwarded and mapped to the same space. Then, the fused slices are stacked in order to form a three-dimensional customized fMRI template with individual pertinence. Finally, in the classic registration algorithm, the difference in the registration accuracy between using a custom fMRI template and different standard spaces is compared, which proves that using a custom template can improve the registration effect to a certain extent. MDPI 2022-08-20 /pmc/articles/PMC9407088/ /pubmed/36010363 http://dx.doi.org/10.3390/diagnostics12082013 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Wang, Zhongyang
Xin, Junchang
Shen, Huixian
Chen, Qi
Wang, Zhiqiong
Wang, Xinlei
Custom 3D fMRI Registration Template Construction Method Based on Time-Series Fusion
title Custom 3D fMRI Registration Template Construction Method Based on Time-Series Fusion
title_full Custom 3D fMRI Registration Template Construction Method Based on Time-Series Fusion
title_fullStr Custom 3D fMRI Registration Template Construction Method Based on Time-Series Fusion
title_full_unstemmed Custom 3D fMRI Registration Template Construction Method Based on Time-Series Fusion
title_short Custom 3D fMRI Registration Template Construction Method Based on Time-Series Fusion
title_sort custom 3d fmri registration template construction method based on time-series fusion
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407088/
https://www.ncbi.nlm.nih.gov/pubmed/36010363
http://dx.doi.org/10.3390/diagnostics12082013
work_keys_str_mv AT wangzhongyang custom3dfmriregistrationtemplateconstructionmethodbasedontimeseriesfusion
AT xinjunchang custom3dfmriregistrationtemplateconstructionmethodbasedontimeseriesfusion
AT shenhuixian custom3dfmriregistrationtemplateconstructionmethodbasedontimeseriesfusion
AT chenqi custom3dfmriregistrationtemplateconstructionmethodbasedontimeseriesfusion
AT wangzhiqiong custom3dfmriregistrationtemplateconstructionmethodbasedontimeseriesfusion
AT wangxinlei custom3dfmriregistrationtemplateconstructionmethodbasedontimeseriesfusion