The Management of Pregnancy Complicated with the Previable Preterm and Preterm Premature Rupture of the Membranes: What about a Limit of Neonatal Viability?—A Review

Preterm premature rupture of the membranes (PPROM) at the limit of viability is associated with low neonatal survival rates and a high rate of neonatal complications in survivors. It carries a major risk of maternal morbidity and mortality. The limit of viability can be defined as the earliest stage...

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Autores principales: Feduniw, Stepan, Gaca, Zuzanna, Malinowska, Olga, Brunets, Weronika, Zgliczyńska, Magdalena, Włodarczyk, Marta, Wójcikiewicz, Anna, Ciebiera, Michał
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407094/
https://www.ncbi.nlm.nih.gov/pubmed/36010375
http://dx.doi.org/10.3390/diagnostics12082025
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author Feduniw, Stepan
Gaca, Zuzanna
Malinowska, Olga
Brunets, Weronika
Zgliczyńska, Magdalena
Włodarczyk, Marta
Wójcikiewicz, Anna
Ciebiera, Michał
author_facet Feduniw, Stepan
Gaca, Zuzanna
Malinowska, Olga
Brunets, Weronika
Zgliczyńska, Magdalena
Włodarczyk, Marta
Wójcikiewicz, Anna
Ciebiera, Michał
author_sort Feduniw, Stepan
collection PubMed
description Preterm premature rupture of the membranes (PPROM) at the limit of viability is associated with low neonatal survival rates and a high rate of neonatal complications in survivors. It carries a major risk of maternal morbidity and mortality. The limit of viability can be defined as the earliest stage of fetal maturity when a fetus has a reasonable chance, although not a high likelihood, for extra-uterine survival. The study reviews available data on preventing preterm delivery caused by the previable PPROM, pregnancy latency, therapeutic options including the use of antibiotics and steroids, neonatal outcomes, and future directions and opportunities.
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spelling pubmed-94070942022-08-26 The Management of Pregnancy Complicated with the Previable Preterm and Preterm Premature Rupture of the Membranes: What about a Limit of Neonatal Viability?—A Review Feduniw, Stepan Gaca, Zuzanna Malinowska, Olga Brunets, Weronika Zgliczyńska, Magdalena Włodarczyk, Marta Wójcikiewicz, Anna Ciebiera, Michał Diagnostics (Basel) Review Preterm premature rupture of the membranes (PPROM) at the limit of viability is associated with low neonatal survival rates and a high rate of neonatal complications in survivors. It carries a major risk of maternal morbidity and mortality. The limit of viability can be defined as the earliest stage of fetal maturity when a fetus has a reasonable chance, although not a high likelihood, for extra-uterine survival. The study reviews available data on preventing preterm delivery caused by the previable PPROM, pregnancy latency, therapeutic options including the use of antibiotics and steroids, neonatal outcomes, and future directions and opportunities. MDPI 2022-08-22 /pmc/articles/PMC9407094/ /pubmed/36010375 http://dx.doi.org/10.3390/diagnostics12082025 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Feduniw, Stepan
Gaca, Zuzanna
Malinowska, Olga
Brunets, Weronika
Zgliczyńska, Magdalena
Włodarczyk, Marta
Wójcikiewicz, Anna
Ciebiera, Michał
The Management of Pregnancy Complicated with the Previable Preterm and Preterm Premature Rupture of the Membranes: What about a Limit of Neonatal Viability?—A Review
title The Management of Pregnancy Complicated with the Previable Preterm and Preterm Premature Rupture of the Membranes: What about a Limit of Neonatal Viability?—A Review
title_full The Management of Pregnancy Complicated with the Previable Preterm and Preterm Premature Rupture of the Membranes: What about a Limit of Neonatal Viability?—A Review
title_fullStr The Management of Pregnancy Complicated with the Previable Preterm and Preterm Premature Rupture of the Membranes: What about a Limit of Neonatal Viability?—A Review
title_full_unstemmed The Management of Pregnancy Complicated with the Previable Preterm and Preterm Premature Rupture of the Membranes: What about a Limit of Neonatal Viability?—A Review
title_short The Management of Pregnancy Complicated with the Previable Preterm and Preterm Premature Rupture of the Membranes: What about a Limit of Neonatal Viability?—A Review
title_sort management of pregnancy complicated with the previable preterm and preterm premature rupture of the membranes: what about a limit of neonatal viability?—a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407094/
https://www.ncbi.nlm.nih.gov/pubmed/36010375
http://dx.doi.org/10.3390/diagnostics12082025
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