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Prediction Model for Hypertension and Diabetes Mellitus Using Korean Public Health Examination Data (2002–2017)

Hypertension and diabetes mellitus are major chronic diseases that are important factors in the management of cardiovascular disease. In order to prevent the occurrence of chronic diseases, proper health management through periodic health check-ups is necessary. The purpose of this study is to deter...

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Autores principales: Jeong, Yong Whi, Jung, Yeojin, Jeong, Hoyeon, Huh, Ji Hye, Sung, Ki-Chul, Shin, Jeong-Hun, Kim, Hyeon Chang, Kim, Jang Young, Kang, Dae Ryong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407141/
https://www.ncbi.nlm.nih.gov/pubmed/36010317
http://dx.doi.org/10.3390/diagnostics12081967
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author Jeong, Yong Whi
Jung, Yeojin
Jeong, Hoyeon
Huh, Ji Hye
Sung, Ki-Chul
Shin, Jeong-Hun
Kim, Hyeon Chang
Kim, Jang Young
Kang, Dae Ryong
author_facet Jeong, Yong Whi
Jung, Yeojin
Jeong, Hoyeon
Huh, Ji Hye
Sung, Ki-Chul
Shin, Jeong-Hun
Kim, Hyeon Chang
Kim, Jang Young
Kang, Dae Ryong
author_sort Jeong, Yong Whi
collection PubMed
description Hypertension and diabetes mellitus are major chronic diseases that are important factors in the management of cardiovascular disease. In order to prevent the occurrence of chronic diseases, proper health management through periodic health check-ups is necessary. The purpose of this study is to determine the incidence of hypertension and diabetes mellitus according to the health check-up, and to develop a predictive model for hypertension and diabetes according to the health check-up. We used the National Health Insurance Corporation database of Korea and checked whether hypertension or diabetes occurred from that date according to the number of health check-ups over the past 10 years. Compared to those who underwent five health check-ups, those who participated in the first screening had hypertension (OR = 2.18, 95% CI = 2.14–2.22), diabetes mellitus (OR = 1.33, 95% CI = 1.30–1.35) and both diseases (OR = 2.46, 95% CI = 2.39–2.53); individuals who underwent 10 screenings had hypertension (OR = 0.86, 95% CI = 0.83–0.88), diabetes mellitus (OR = 0.83, 95% CI = 0.81–0.85) and both diseases (OR = 0.83, 95% CI = 0.79–0.87). Individuals who attended fewer than five screenings compared with individuals who attended five or more screenings had hypertension (OR = 1.61, 95% CI = 1.59–1.62; AUC = 0.66), diabetes mellitus (OR = 1.21, 95% CI = 1.20–1.22; AUC = 0.59) and both diseases (OR = 1.75, 95% CI = 1.72–1.78, AUC = 0.63). The machine learning-based prediction model using XGBoost showed higher performance in all datasets than the conventional logistic regression model in predicting hypertension (accuracy, 0.828 vs. 0.628; F1-score, 0.800 vs. 0.633; AUC, 828 vs. 0.630), diabetes mellitus (accuracy, 0.707 vs. 0.575; F1-score, 0.663 vs. 0.576; AUC, 0.710 vs. 0.575) and both diseases (accuracy, 0.950 vs. 0.612; F1-score, 0.950 vs. 0.614; AUC, 0.952 vs. 0.612). It was found that health check-up had a great influence on the occurrence of hypertension and diabetes, and screening frequency was more important than other factors in the variable importances.
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spelling pubmed-94071412022-08-26 Prediction Model for Hypertension and Diabetes Mellitus Using Korean Public Health Examination Data (2002–2017) Jeong, Yong Whi Jung, Yeojin Jeong, Hoyeon Huh, Ji Hye Sung, Ki-Chul Shin, Jeong-Hun Kim, Hyeon Chang Kim, Jang Young Kang, Dae Ryong Diagnostics (Basel) Article Hypertension and diabetes mellitus are major chronic diseases that are important factors in the management of cardiovascular disease. In order to prevent the occurrence of chronic diseases, proper health management through periodic health check-ups is necessary. The purpose of this study is to determine the incidence of hypertension and diabetes mellitus according to the health check-up, and to develop a predictive model for hypertension and diabetes according to the health check-up. We used the National Health Insurance Corporation database of Korea and checked whether hypertension or diabetes occurred from that date according to the number of health check-ups over the past 10 years. Compared to those who underwent five health check-ups, those who participated in the first screening had hypertension (OR = 2.18, 95% CI = 2.14–2.22), diabetes mellitus (OR = 1.33, 95% CI = 1.30–1.35) and both diseases (OR = 2.46, 95% CI = 2.39–2.53); individuals who underwent 10 screenings had hypertension (OR = 0.86, 95% CI = 0.83–0.88), diabetes mellitus (OR = 0.83, 95% CI = 0.81–0.85) and both diseases (OR = 0.83, 95% CI = 0.79–0.87). Individuals who attended fewer than five screenings compared with individuals who attended five or more screenings had hypertension (OR = 1.61, 95% CI = 1.59–1.62; AUC = 0.66), diabetes mellitus (OR = 1.21, 95% CI = 1.20–1.22; AUC = 0.59) and both diseases (OR = 1.75, 95% CI = 1.72–1.78, AUC = 0.63). The machine learning-based prediction model using XGBoost showed higher performance in all datasets than the conventional logistic regression model in predicting hypertension (accuracy, 0.828 vs. 0.628; F1-score, 0.800 vs. 0.633; AUC, 828 vs. 0.630), diabetes mellitus (accuracy, 0.707 vs. 0.575; F1-score, 0.663 vs. 0.576; AUC, 0.710 vs. 0.575) and both diseases (accuracy, 0.950 vs. 0.612; F1-score, 0.950 vs. 0.614; AUC, 0.952 vs. 0.612). It was found that health check-up had a great influence on the occurrence of hypertension and diabetes, and screening frequency was more important than other factors in the variable importances. MDPI 2022-08-14 /pmc/articles/PMC9407141/ /pubmed/36010317 http://dx.doi.org/10.3390/diagnostics12081967 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Jeong, Yong Whi
Jung, Yeojin
Jeong, Hoyeon
Huh, Ji Hye
Sung, Ki-Chul
Shin, Jeong-Hun
Kim, Hyeon Chang
Kim, Jang Young
Kang, Dae Ryong
Prediction Model for Hypertension and Diabetes Mellitus Using Korean Public Health Examination Data (2002–2017)
title Prediction Model for Hypertension and Diabetes Mellitus Using Korean Public Health Examination Data (2002–2017)
title_full Prediction Model for Hypertension and Diabetes Mellitus Using Korean Public Health Examination Data (2002–2017)
title_fullStr Prediction Model for Hypertension and Diabetes Mellitus Using Korean Public Health Examination Data (2002–2017)
title_full_unstemmed Prediction Model for Hypertension and Diabetes Mellitus Using Korean Public Health Examination Data (2002–2017)
title_short Prediction Model for Hypertension and Diabetes Mellitus Using Korean Public Health Examination Data (2002–2017)
title_sort prediction model for hypertension and diabetes mellitus using korean public health examination data (2002–2017)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407141/
https://www.ncbi.nlm.nih.gov/pubmed/36010317
http://dx.doi.org/10.3390/diagnostics12081967
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