Prediction of the Effects of Missense Mutations on Human Myeloperoxidase Protein Stability Using In Silico Saturation Mutagenesis

Myeloperoxidase (MPO) is a heme peroxidase with microbicidal properties. MPO plays a role in the host’s innate immunity by producing reactive oxygen species inside the cell against foreign organisms. However, there is little functional evidence linking missense mutations to human diseases. We utiliz...

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Detalles Bibliográficos
Autores principales: Sobitan, Adebiyi, Edwards, William, Jalal, Md Shah, Kolawole, Ayanfeoluwa, Ullah, Hemayet, Duttaroy, Atanu, Li, Jiang, Teng, Shaolei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407467/
https://www.ncbi.nlm.nih.gov/pubmed/36011324
http://dx.doi.org/10.3390/genes13081412

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