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Sustainable Development and Storage Stability of Orange By-Products Extract Using Natural Deep Eutectic Solvents

The citrus industry produces large amounts of waste rich in bioactive compounds that have important effects on human health. Their extraction was performed using organic solvents, and a greener alternative to those solvents are natural deep eutectic solvents (NADES). The present study aimed to obtai...

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Autores principales: Gómez-Urios, Clara, Viñas-Ospino, Adriana, Puchades-Colera, Pablo, López-Malo, Daniel, Frígola, Ana, Esteve, María José, Blesa, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407522/
https://www.ncbi.nlm.nih.gov/pubmed/36010457
http://dx.doi.org/10.3390/foods11162457
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author Gómez-Urios, Clara
Viñas-Ospino, Adriana
Puchades-Colera, Pablo
López-Malo, Daniel
Frígola, Ana
Esteve, María José
Blesa, Jesús
author_facet Gómez-Urios, Clara
Viñas-Ospino, Adriana
Puchades-Colera, Pablo
López-Malo, Daniel
Frígola, Ana
Esteve, María José
Blesa, Jesús
author_sort Gómez-Urios, Clara
collection PubMed
description The citrus industry produces large amounts of waste rich in bioactive compounds that have important effects on human health. Their extraction was performed using organic solvents, and a greener alternative to those solvents are natural deep eutectic solvents (NADES). The present study aimed to obtain and optimize extracts rich in polyphenols and flavonoids from orange peels using NADES and monitor polyphenol stability in the extracts for 30 days. The software COSMOtherm (conductor-like screening model) was used to screen fourteen NADES. The most promising solvents were lactic acid:glucose (LA:Glu) with an extraction yield of 1932 ± 7.83 mgGAE/100 gdw for TPC (total polyphenol content) and 82.7 ± 3.0 mg/100 gdw for TFC (total flavonoid content) and in the case of L-proline:malic acid (LP:MA) was 2164 ± 5.17 mgGAE/100 gdw for TPC and 97.0 ± 1.65 mg/100 gdw for TFC. The extraction process using LA:Glu and LP:MA was optimized, and the results showed that the selected variables (%NADES, solid:liquid ratio, and extraction time) had a significant influence on the extraction of TPC and TFC. Results showed that NADES improve the stability of TPC. These findings revealed that NADES are efficient for the extraction of bioactive compounds from orange by-products, and these extracts can represent an alternative for the food industry to enrich food products with natural ingredients.
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spelling pubmed-94075222022-08-26 Sustainable Development and Storage Stability of Orange By-Products Extract Using Natural Deep Eutectic Solvents Gómez-Urios, Clara Viñas-Ospino, Adriana Puchades-Colera, Pablo López-Malo, Daniel Frígola, Ana Esteve, María José Blesa, Jesús Foods Article The citrus industry produces large amounts of waste rich in bioactive compounds that have important effects on human health. Their extraction was performed using organic solvents, and a greener alternative to those solvents are natural deep eutectic solvents (NADES). The present study aimed to obtain and optimize extracts rich in polyphenols and flavonoids from orange peels using NADES and monitor polyphenol stability in the extracts for 30 days. The software COSMOtherm (conductor-like screening model) was used to screen fourteen NADES. The most promising solvents were lactic acid:glucose (LA:Glu) with an extraction yield of 1932 ± 7.83 mgGAE/100 gdw for TPC (total polyphenol content) and 82.7 ± 3.0 mg/100 gdw for TFC (total flavonoid content) and in the case of L-proline:malic acid (LP:MA) was 2164 ± 5.17 mgGAE/100 gdw for TPC and 97.0 ± 1.65 mg/100 gdw for TFC. The extraction process using LA:Glu and LP:MA was optimized, and the results showed that the selected variables (%NADES, solid:liquid ratio, and extraction time) had a significant influence on the extraction of TPC and TFC. Results showed that NADES improve the stability of TPC. These findings revealed that NADES are efficient for the extraction of bioactive compounds from orange by-products, and these extracts can represent an alternative for the food industry to enrich food products with natural ingredients. MDPI 2022-08-15 /pmc/articles/PMC9407522/ /pubmed/36010457 http://dx.doi.org/10.3390/foods11162457 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Gómez-Urios, Clara
Viñas-Ospino, Adriana
Puchades-Colera, Pablo
López-Malo, Daniel
Frígola, Ana
Esteve, María José
Blesa, Jesús
Sustainable Development and Storage Stability of Orange By-Products Extract Using Natural Deep Eutectic Solvents
title Sustainable Development and Storage Stability of Orange By-Products Extract Using Natural Deep Eutectic Solvents
title_full Sustainable Development and Storage Stability of Orange By-Products Extract Using Natural Deep Eutectic Solvents
title_fullStr Sustainable Development and Storage Stability of Orange By-Products Extract Using Natural Deep Eutectic Solvents
title_full_unstemmed Sustainable Development and Storage Stability of Orange By-Products Extract Using Natural Deep Eutectic Solvents
title_short Sustainable Development and Storage Stability of Orange By-Products Extract Using Natural Deep Eutectic Solvents
title_sort sustainable development and storage stability of orange by-products extract using natural deep eutectic solvents
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407522/
https://www.ncbi.nlm.nih.gov/pubmed/36010457
http://dx.doi.org/10.3390/foods11162457
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