Serine 408 phosphorylation is a molecular switch that regulates structure and function of the occludin α-helical bundle

Occludin is a tetramembrane-spanning tight junction protein. The long C-terminal cytoplasmic domain, which represents nearly half of occludin sequence, includes a distal bundle of three α-helices that mediates interactions with other tight junction components. A short unstructured region just proxim...

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Detalles Bibliográficos
Autores principales: Srivastava, Atul K., Venkata, Bharat Somireddy, Sweat, Yan Y., Rizzo, Heather R., Jean-François, Léa, Zuo, Li, Kurgan, Kathleen W., Moore, Patrick, Shashikanth, Nitesh, Smok, Izabela, Sachleben, Joseph R., Turner, Jerrold R., Meredith, Stephen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407527/
https://www.ncbi.nlm.nih.gov/pubmed/35969745
http://dx.doi.org/10.1073/pnas.2204618119

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