Global patterns of antigen receptor repertoire disruption across adaptive immune compartments in COVID-19

Whereas pathogen-specific T and B cells are a primary focus of interest during infectious disease, we have used COVID-19 to ask whether their emergence comes at a cost of broader B cell and T cell repertoire disruption. We applied a genomic DNA-based approach to concurrently study the immunoglobulin...

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Detalles Bibliográficos
Autores principales: Joseph, Magdalene, Wu, Yin, Dannebaum, Richard, Rubelt, Florian, Zlatareva, Iva, Lorenc, Anna, Du, Zhipei Gracie, Davies, Daniel, Kyle-Cezar, Fernanda, Das, Abhishek, Gee, Sarah, Seow, Jeffrey, Graham, Carl, Telman, Dilduz, Bermejo, Clara, Lin, Hai, Asgharian, Hosseinali, Laing, Adam G., del Molino del Barrio, Irene, Monin, Leticia, Muñoz-Ruiz, Miguel, McKenzie, Duncan R., Hayday, Thomas S., Francos-Quijorna, Isaac, Kamdar, Shraddha, Davis, Richard, Sofra, Vasiliki, Cano, Florencia, Theodoridis, Efstathios, Martinez, Lauren, Merrick, Blair, Bisnauthsing, Karen, Brooks, Kate, Edgeworth, Jonathan, Cason, John, Mant, Christine, Doores, Katie J., Vantourout, Pierre, Luong, Khai, Berka, Jan, Hayday, Adrian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407655/
https://www.ncbi.nlm.nih.gov/pubmed/35943978
http://dx.doi.org/10.1073/pnas.2201541119

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