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High Levels of Outpatient Antibiotic Prescription at a District Hospital in Ghana: Results of a Cross Sectional Study
Background: Monitoring of antibiotic prescription practices in hospitals is essential to assess and facilitate appropriate use. This is relevant to halt the progression of antimicrobial resistance. Methods: Assessment of antibiotic prescribing patterns and completeness of antibiotic prescriptions am...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407799/ https://www.ncbi.nlm.nih.gov/pubmed/36011917 http://dx.doi.org/10.3390/ijerph191610286 |
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author | Amponsah, Obed Kwabena Offe Nagaraja, Sharath Burugina Ayisi-Boateng, Nana Kwame Nair, Divya Muradyan, Karlos Asense, Phanuel Seli Wusu-Ansah, Osei Kwaku Terry, Robert Fraser Khogali, Mohammed Buabeng, Kwame Ohene |
author_facet | Amponsah, Obed Kwabena Offe Nagaraja, Sharath Burugina Ayisi-Boateng, Nana Kwame Nair, Divya Muradyan, Karlos Asense, Phanuel Seli Wusu-Ansah, Osei Kwaku Terry, Robert Fraser Khogali, Mohammed Buabeng, Kwame Ohene |
author_sort | Amponsah, Obed Kwabena Offe |
collection | PubMed |
description | Background: Monitoring of antibiotic prescription practices in hospitals is essential to assess and facilitate appropriate use. This is relevant to halt the progression of antimicrobial resistance. Methods: Assessment of antibiotic prescribing patterns and completeness of antibiotic prescriptions among out-patients in 2021 was conducted at the University Hospital of Kwame Nkrumah University of Science and Technology in the Ashanti region of Ghana. We reviewed electronic medical records (EMR) of 49,660 patients who had 110,280 encounters in the year. Results: The patient encounters yielded 350,149 prescriptions. Every month, 33–36% of patient encounters resulted in antibiotic prescription, higher than the World Health Organization’s (WHO) recommended optimum of 27%. Almost half of the antibiotics prescribed belonged to WHO’s Watch group. Amoxicillin–clavulanic acid (50%), azithromycin (29%), ciprofloxacin (28%), metronidazole (21%), and cefuroxime (20%) were the most prescribed antibiotics. Antibiotic prescribing parameters (indication, name of drug, duration, dose, route, and frequency) were documented in almost all prescriptions. Conclusions: Extending antimicrobial stewardship to the out-patient settings by developing standard treatment guidelines, an out-patient specific drug formulary, and antibiograms can promote rational antibiotic use at the hospital. The EMR system of the hospital is a valuable tool for monitoring prescriptions that can be leveraged for future audits. |
format | Online Article Text |
id | pubmed-9407799 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-94077992022-08-26 High Levels of Outpatient Antibiotic Prescription at a District Hospital in Ghana: Results of a Cross Sectional Study Amponsah, Obed Kwabena Offe Nagaraja, Sharath Burugina Ayisi-Boateng, Nana Kwame Nair, Divya Muradyan, Karlos Asense, Phanuel Seli Wusu-Ansah, Osei Kwaku Terry, Robert Fraser Khogali, Mohammed Buabeng, Kwame Ohene Int J Environ Res Public Health Article Background: Monitoring of antibiotic prescription practices in hospitals is essential to assess and facilitate appropriate use. This is relevant to halt the progression of antimicrobial resistance. Methods: Assessment of antibiotic prescribing patterns and completeness of antibiotic prescriptions among out-patients in 2021 was conducted at the University Hospital of Kwame Nkrumah University of Science and Technology in the Ashanti region of Ghana. We reviewed electronic medical records (EMR) of 49,660 patients who had 110,280 encounters in the year. Results: The patient encounters yielded 350,149 prescriptions. Every month, 33–36% of patient encounters resulted in antibiotic prescription, higher than the World Health Organization’s (WHO) recommended optimum of 27%. Almost half of the antibiotics prescribed belonged to WHO’s Watch group. Amoxicillin–clavulanic acid (50%), azithromycin (29%), ciprofloxacin (28%), metronidazole (21%), and cefuroxime (20%) were the most prescribed antibiotics. Antibiotic prescribing parameters (indication, name of drug, duration, dose, route, and frequency) were documented in almost all prescriptions. Conclusions: Extending antimicrobial stewardship to the out-patient settings by developing standard treatment guidelines, an out-patient specific drug formulary, and antibiograms can promote rational antibiotic use at the hospital. The EMR system of the hospital is a valuable tool for monitoring prescriptions that can be leveraged for future audits. MDPI 2022-08-18 /pmc/articles/PMC9407799/ /pubmed/36011917 http://dx.doi.org/10.3390/ijerph191610286 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Amponsah, Obed Kwabena Offe Nagaraja, Sharath Burugina Ayisi-Boateng, Nana Kwame Nair, Divya Muradyan, Karlos Asense, Phanuel Seli Wusu-Ansah, Osei Kwaku Terry, Robert Fraser Khogali, Mohammed Buabeng, Kwame Ohene High Levels of Outpatient Antibiotic Prescription at a District Hospital in Ghana: Results of a Cross Sectional Study |
title | High Levels of Outpatient Antibiotic Prescription at a District Hospital in Ghana: Results of a Cross Sectional Study |
title_full | High Levels of Outpatient Antibiotic Prescription at a District Hospital in Ghana: Results of a Cross Sectional Study |
title_fullStr | High Levels of Outpatient Antibiotic Prescription at a District Hospital in Ghana: Results of a Cross Sectional Study |
title_full_unstemmed | High Levels of Outpatient Antibiotic Prescription at a District Hospital in Ghana: Results of a Cross Sectional Study |
title_short | High Levels of Outpatient Antibiotic Prescription at a District Hospital in Ghana: Results of a Cross Sectional Study |
title_sort | high levels of outpatient antibiotic prescription at a district hospital in ghana: results of a cross sectional study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407799/ https://www.ncbi.nlm.nih.gov/pubmed/36011917 http://dx.doi.org/10.3390/ijerph191610286 |
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