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High Levels of Outpatient Antibiotic Prescription at a District Hospital in Ghana: Results of a Cross Sectional Study

Background: Monitoring of antibiotic prescription practices in hospitals is essential to assess and facilitate appropriate use. This is relevant to halt the progression of antimicrobial resistance. Methods: Assessment of antibiotic prescribing patterns and completeness of antibiotic prescriptions am...

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Autores principales: Amponsah, Obed Kwabena Offe, Nagaraja, Sharath Burugina, Ayisi-Boateng, Nana Kwame, Nair, Divya, Muradyan, Karlos, Asense, Phanuel Seli, Wusu-Ansah, Osei Kwaku, Terry, Robert Fraser, Khogali, Mohammed, Buabeng, Kwame Ohene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407799/
https://www.ncbi.nlm.nih.gov/pubmed/36011917
http://dx.doi.org/10.3390/ijerph191610286
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author Amponsah, Obed Kwabena Offe
Nagaraja, Sharath Burugina
Ayisi-Boateng, Nana Kwame
Nair, Divya
Muradyan, Karlos
Asense, Phanuel Seli
Wusu-Ansah, Osei Kwaku
Terry, Robert Fraser
Khogali, Mohammed
Buabeng, Kwame Ohene
author_facet Amponsah, Obed Kwabena Offe
Nagaraja, Sharath Burugina
Ayisi-Boateng, Nana Kwame
Nair, Divya
Muradyan, Karlos
Asense, Phanuel Seli
Wusu-Ansah, Osei Kwaku
Terry, Robert Fraser
Khogali, Mohammed
Buabeng, Kwame Ohene
author_sort Amponsah, Obed Kwabena Offe
collection PubMed
description Background: Monitoring of antibiotic prescription practices in hospitals is essential to assess and facilitate appropriate use. This is relevant to halt the progression of antimicrobial resistance. Methods: Assessment of antibiotic prescribing patterns and completeness of antibiotic prescriptions among out-patients in 2021 was conducted at the University Hospital of Kwame Nkrumah University of Science and Technology in the Ashanti region of Ghana. We reviewed electronic medical records (EMR) of 49,660 patients who had 110,280 encounters in the year. Results: The patient encounters yielded 350,149 prescriptions. Every month, 33–36% of patient encounters resulted in antibiotic prescription, higher than the World Health Organization’s (WHO) recommended optimum of 27%. Almost half of the antibiotics prescribed belonged to WHO’s Watch group. Amoxicillin–clavulanic acid (50%), azithromycin (29%), ciprofloxacin (28%), metronidazole (21%), and cefuroxime (20%) were the most prescribed antibiotics. Antibiotic prescribing parameters (indication, name of drug, duration, dose, route, and frequency) were documented in almost all prescriptions. Conclusions: Extending antimicrobial stewardship to the out-patient settings by developing standard treatment guidelines, an out-patient specific drug formulary, and antibiograms can promote rational antibiotic use at the hospital. The EMR system of the hospital is a valuable tool for monitoring prescriptions that can be leveraged for future audits.
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spelling pubmed-94077992022-08-26 High Levels of Outpatient Antibiotic Prescription at a District Hospital in Ghana: Results of a Cross Sectional Study Amponsah, Obed Kwabena Offe Nagaraja, Sharath Burugina Ayisi-Boateng, Nana Kwame Nair, Divya Muradyan, Karlos Asense, Phanuel Seli Wusu-Ansah, Osei Kwaku Terry, Robert Fraser Khogali, Mohammed Buabeng, Kwame Ohene Int J Environ Res Public Health Article Background: Monitoring of antibiotic prescription practices in hospitals is essential to assess and facilitate appropriate use. This is relevant to halt the progression of antimicrobial resistance. Methods: Assessment of antibiotic prescribing patterns and completeness of antibiotic prescriptions among out-patients in 2021 was conducted at the University Hospital of Kwame Nkrumah University of Science and Technology in the Ashanti region of Ghana. We reviewed electronic medical records (EMR) of 49,660 patients who had 110,280 encounters in the year. Results: The patient encounters yielded 350,149 prescriptions. Every month, 33–36% of patient encounters resulted in antibiotic prescription, higher than the World Health Organization’s (WHO) recommended optimum of 27%. Almost half of the antibiotics prescribed belonged to WHO’s Watch group. Amoxicillin–clavulanic acid (50%), azithromycin (29%), ciprofloxacin (28%), metronidazole (21%), and cefuroxime (20%) were the most prescribed antibiotics. Antibiotic prescribing parameters (indication, name of drug, duration, dose, route, and frequency) were documented in almost all prescriptions. Conclusions: Extending antimicrobial stewardship to the out-patient settings by developing standard treatment guidelines, an out-patient specific drug formulary, and antibiograms can promote rational antibiotic use at the hospital. The EMR system of the hospital is a valuable tool for monitoring prescriptions that can be leveraged for future audits. MDPI 2022-08-18 /pmc/articles/PMC9407799/ /pubmed/36011917 http://dx.doi.org/10.3390/ijerph191610286 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Amponsah, Obed Kwabena Offe
Nagaraja, Sharath Burugina
Ayisi-Boateng, Nana Kwame
Nair, Divya
Muradyan, Karlos
Asense, Phanuel Seli
Wusu-Ansah, Osei Kwaku
Terry, Robert Fraser
Khogali, Mohammed
Buabeng, Kwame Ohene
High Levels of Outpatient Antibiotic Prescription at a District Hospital in Ghana: Results of a Cross Sectional Study
title High Levels of Outpatient Antibiotic Prescription at a District Hospital in Ghana: Results of a Cross Sectional Study
title_full High Levels of Outpatient Antibiotic Prescription at a District Hospital in Ghana: Results of a Cross Sectional Study
title_fullStr High Levels of Outpatient Antibiotic Prescription at a District Hospital in Ghana: Results of a Cross Sectional Study
title_full_unstemmed High Levels of Outpatient Antibiotic Prescription at a District Hospital in Ghana: Results of a Cross Sectional Study
title_short High Levels of Outpatient Antibiotic Prescription at a District Hospital in Ghana: Results of a Cross Sectional Study
title_sort high levels of outpatient antibiotic prescription at a district hospital in ghana: results of a cross sectional study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407799/
https://www.ncbi.nlm.nih.gov/pubmed/36011917
http://dx.doi.org/10.3390/ijerph191610286
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