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Substantial Impairment of Quality of Life during COVID-19 Pandemic in Patients with Advanced Rectal Cancer

The aim of this study was to analyze the quality of life of patients with advanced rectal cancer before and during the COVID-19 pandemic and to determine whether the pandemic affected patients’ quality of life. The study included 389 patients and was performed from May 2010 to June 2021. The fifteen...

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Autores principales: Dennison, Irene, Schweizer, Claudia, Fitz, Tim, Blasko, Daniel, Sörgel, Christopher, Kallies, Annett, Schmidt, Linda, Fietkau, Rainer, Distel, Luitpold Valentin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407989/
https://www.ncbi.nlm.nih.gov/pubmed/36011170
http://dx.doi.org/10.3390/healthcare10081513
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author Dennison, Irene
Schweizer, Claudia
Fitz, Tim
Blasko, Daniel
Sörgel, Christopher
Kallies, Annett
Schmidt, Linda
Fietkau, Rainer
Distel, Luitpold Valentin
author_facet Dennison, Irene
Schweizer, Claudia
Fitz, Tim
Blasko, Daniel
Sörgel, Christopher
Kallies, Annett
Schmidt, Linda
Fietkau, Rainer
Distel, Luitpold Valentin
author_sort Dennison, Irene
collection PubMed
description The aim of this study was to analyze the quality of life of patients with advanced rectal cancer before and during the COVID-19 pandemic and to determine whether the pandemic affected patients’ quality of life. The study included 389 patients and was performed from May 2010 to June 2021. The fifteen months from March 2020 to June 2021 were categorized as the COVID-19 period. Patients were surveyed using the QLQ-C30 and QLQ-CR38 questionnaires. The questionnaires were used at different phases of radiochemotherapy: prior to RCT (day 1), during RCT (day 14), at the end of RCT (day 35), and prior to mesorectal surgery (day 70). Scores were formed from the questions. In addition, scores were analyzed for different age groups (<64 and >64) and sexes (female and male). Overall, patients reported lower functional scores and higher symptom scores during the pandemic than before the pandemic. Although it had been expected that older and younger patients would differ clearly, there were only minor differences. The comparison between the two sexes showed very different scores, with female patients having lower functional scores and higher symptom scores than male patients before and especially during COVID-19. In conclusion, age does not play a major role in quality of life, but sex does play an important role in perception of functioning and symptoms. COVID-19 also had a major impact on patients’ lives, as it was a very isolating and stressful time for everyone, especially cancer patients, which was reflected in worsening scores.
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spelling pubmed-94079892022-08-26 Substantial Impairment of Quality of Life during COVID-19 Pandemic in Patients with Advanced Rectal Cancer Dennison, Irene Schweizer, Claudia Fitz, Tim Blasko, Daniel Sörgel, Christopher Kallies, Annett Schmidt, Linda Fietkau, Rainer Distel, Luitpold Valentin Healthcare (Basel) Article The aim of this study was to analyze the quality of life of patients with advanced rectal cancer before and during the COVID-19 pandemic and to determine whether the pandemic affected patients’ quality of life. The study included 389 patients and was performed from May 2010 to June 2021. The fifteen months from March 2020 to June 2021 were categorized as the COVID-19 period. Patients were surveyed using the QLQ-C30 and QLQ-CR38 questionnaires. The questionnaires were used at different phases of radiochemotherapy: prior to RCT (day 1), during RCT (day 14), at the end of RCT (day 35), and prior to mesorectal surgery (day 70). Scores were formed from the questions. In addition, scores were analyzed for different age groups (<64 and >64) and sexes (female and male). Overall, patients reported lower functional scores and higher symptom scores during the pandemic than before the pandemic. Although it had been expected that older and younger patients would differ clearly, there were only minor differences. The comparison between the two sexes showed very different scores, with female patients having lower functional scores and higher symptom scores than male patients before and especially during COVID-19. In conclusion, age does not play a major role in quality of life, but sex does play an important role in perception of functioning and symptoms. COVID-19 also had a major impact on patients’ lives, as it was a very isolating and stressful time for everyone, especially cancer patients, which was reflected in worsening scores. MDPI 2022-08-11 /pmc/articles/PMC9407989/ /pubmed/36011170 http://dx.doi.org/10.3390/healthcare10081513 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Dennison, Irene
Schweizer, Claudia
Fitz, Tim
Blasko, Daniel
Sörgel, Christopher
Kallies, Annett
Schmidt, Linda
Fietkau, Rainer
Distel, Luitpold Valentin
Substantial Impairment of Quality of Life during COVID-19 Pandemic in Patients with Advanced Rectal Cancer
title Substantial Impairment of Quality of Life during COVID-19 Pandemic in Patients with Advanced Rectal Cancer
title_full Substantial Impairment of Quality of Life during COVID-19 Pandemic in Patients with Advanced Rectal Cancer
title_fullStr Substantial Impairment of Quality of Life during COVID-19 Pandemic in Patients with Advanced Rectal Cancer
title_full_unstemmed Substantial Impairment of Quality of Life during COVID-19 Pandemic in Patients with Advanced Rectal Cancer
title_short Substantial Impairment of Quality of Life during COVID-19 Pandemic in Patients with Advanced Rectal Cancer
title_sort substantial impairment of quality of life during covid-19 pandemic in patients with advanced rectal cancer
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407989/
https://www.ncbi.nlm.nih.gov/pubmed/36011170
http://dx.doi.org/10.3390/healthcare10081513
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