The Clinical Significance of Urinary Retinol-Binding Protein 4: A Review

Effective biomarkers for early diagnosis, prognostication, and monitoring in renal diseases (in general) comprise an unmet need. Urinary retinol-binding protein 4, which is the most sensitive indicator of renal tubular damage, holds great promise as a universal biomarker for renal pathologies, in wh...

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Autores principales: Ratajczyk, Krzysztof, Konieczny, Andrzej, Czekaj, Adrian, Piotrów, Paweł, Fiutowski, Marek, Krakowska, Kornelia, Kowal, Paweł, Witkiewicz, Wojciech, Marek-Bukowiec, Karolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408023/
https://www.ncbi.nlm.nih.gov/pubmed/36011513
http://dx.doi.org/10.3390/ijerph19169878
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author Ratajczyk, Krzysztof
Konieczny, Andrzej
Czekaj, Adrian
Piotrów, Paweł
Fiutowski, Marek
Krakowska, Kornelia
Kowal, Paweł
Witkiewicz, Wojciech
Marek-Bukowiec, Karolina
author_facet Ratajczyk, Krzysztof
Konieczny, Andrzej
Czekaj, Adrian
Piotrów, Paweł
Fiutowski, Marek
Krakowska, Kornelia
Kowal, Paweł
Witkiewicz, Wojciech
Marek-Bukowiec, Karolina
author_sort Ratajczyk, Krzysztof
collection PubMed
description Effective biomarkers for early diagnosis, prognostication, and monitoring in renal diseases (in general) comprise an unmet need. Urinary retinol-binding protein 4, which is the most sensitive indicator of renal tubular damage, holds great promise as a universal biomarker for renal pathologies, in which tubular injury is the driving force. Here, we summarize the most important existing data on the associations between urinary retinol-binding protein 4 and renal diseases and highlight the untapped potential of retinol-binding protein 4 in clinical use.
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spelling pubmed-94080232022-08-26 The Clinical Significance of Urinary Retinol-Binding Protein 4: A Review Ratajczyk, Krzysztof Konieczny, Andrzej Czekaj, Adrian Piotrów, Paweł Fiutowski, Marek Krakowska, Kornelia Kowal, Paweł Witkiewicz, Wojciech Marek-Bukowiec, Karolina Int J Environ Res Public Health Review Effective biomarkers for early diagnosis, prognostication, and monitoring in renal diseases (in general) comprise an unmet need. Urinary retinol-binding protein 4, which is the most sensitive indicator of renal tubular damage, holds great promise as a universal biomarker for renal pathologies, in which tubular injury is the driving force. Here, we summarize the most important existing data on the associations between urinary retinol-binding protein 4 and renal diseases and highlight the untapped potential of retinol-binding protein 4 in clinical use. MDPI 2022-08-11 /pmc/articles/PMC9408023/ /pubmed/36011513 http://dx.doi.org/10.3390/ijerph19169878 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ratajczyk, Krzysztof
Konieczny, Andrzej
Czekaj, Adrian
Piotrów, Paweł
Fiutowski, Marek
Krakowska, Kornelia
Kowal, Paweł
Witkiewicz, Wojciech
Marek-Bukowiec, Karolina
The Clinical Significance of Urinary Retinol-Binding Protein 4: A Review
title The Clinical Significance of Urinary Retinol-Binding Protein 4: A Review
title_full The Clinical Significance of Urinary Retinol-Binding Protein 4: A Review
title_fullStr The Clinical Significance of Urinary Retinol-Binding Protein 4: A Review
title_full_unstemmed The Clinical Significance of Urinary Retinol-Binding Protein 4: A Review
title_short The Clinical Significance of Urinary Retinol-Binding Protein 4: A Review
title_sort clinical significance of urinary retinol-binding protein 4: a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408023/
https://www.ncbi.nlm.nih.gov/pubmed/36011513
http://dx.doi.org/10.3390/ijerph19169878
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