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Gout as a Risk Factor for Age-Related Macular Degeneration in Taiwanese Adults—A Population-Based Study in Taiwan

The relationship between gout and age-related macular degeneration (AMD) was suggested in previous literature but has yet to be accepted fully among physicians. This study aimed to explore the effect of gout on the development of age-related macular degeneration in Taiwan. A retrospective cohort stu...

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Autores principales: Hsu, Min-Huei, Hsu, Chia-An, Lai, Shih-Chung, Yen, Ju-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408113/
https://www.ncbi.nlm.nih.gov/pubmed/36011777
http://dx.doi.org/10.3390/ijerph191610142
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author Hsu, Min-Huei
Hsu, Chia-An
Lai, Shih-Chung
Yen, Ju-Chuan
author_facet Hsu, Min-Huei
Hsu, Chia-An
Lai, Shih-Chung
Yen, Ju-Chuan
author_sort Hsu, Min-Huei
collection PubMed
description The relationship between gout and age-related macular degeneration (AMD) was suggested in previous literature but has yet to be accepted fully among physicians. This study aimed to explore the effect of gout on the development of age-related macular degeneration in Taiwan. A retrospective cohort study was conducted using Taiwan’s National Health Insurance Database that includes a 2-million-persons dataset. The crude hazard ratio, Kaplan–Meier plot, and separate cox proportional hazard ratio were utilized to demonstrate the effect of gout on the development of age-related macular degeneration. The crude hazard ratio for gout patients developing AMD was 1.55 and the adjusted hazard ratio 1.20. In conclusion, gout is a risk factor for developing AMD, and achieving good disease management is therefore essential for preventing AMD from occurring.
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spelling pubmed-94081132022-08-26 Gout as a Risk Factor for Age-Related Macular Degeneration in Taiwanese Adults—A Population-Based Study in Taiwan Hsu, Min-Huei Hsu, Chia-An Lai, Shih-Chung Yen, Ju-Chuan Int J Environ Res Public Health Article The relationship between gout and age-related macular degeneration (AMD) was suggested in previous literature but has yet to be accepted fully among physicians. This study aimed to explore the effect of gout on the development of age-related macular degeneration in Taiwan. A retrospective cohort study was conducted using Taiwan’s National Health Insurance Database that includes a 2-million-persons dataset. The crude hazard ratio, Kaplan–Meier plot, and separate cox proportional hazard ratio were utilized to demonstrate the effect of gout on the development of age-related macular degeneration. The crude hazard ratio for gout patients developing AMD was 1.55 and the adjusted hazard ratio 1.20. In conclusion, gout is a risk factor for developing AMD, and achieving good disease management is therefore essential for preventing AMD from occurring. MDPI 2022-08-16 /pmc/articles/PMC9408113/ /pubmed/36011777 http://dx.doi.org/10.3390/ijerph191610142 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Hsu, Min-Huei
Hsu, Chia-An
Lai, Shih-Chung
Yen, Ju-Chuan
Gout as a Risk Factor for Age-Related Macular Degeneration in Taiwanese Adults—A Population-Based Study in Taiwan
title Gout as a Risk Factor for Age-Related Macular Degeneration in Taiwanese Adults—A Population-Based Study in Taiwan
title_full Gout as a Risk Factor for Age-Related Macular Degeneration in Taiwanese Adults—A Population-Based Study in Taiwan
title_fullStr Gout as a Risk Factor for Age-Related Macular Degeneration in Taiwanese Adults—A Population-Based Study in Taiwan
title_full_unstemmed Gout as a Risk Factor for Age-Related Macular Degeneration in Taiwanese Adults—A Population-Based Study in Taiwan
title_short Gout as a Risk Factor for Age-Related Macular Degeneration in Taiwanese Adults—A Population-Based Study in Taiwan
title_sort gout as a risk factor for age-related macular degeneration in taiwanese adults—a population-based study in taiwan
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408113/
https://www.ncbi.nlm.nih.gov/pubmed/36011777
http://dx.doi.org/10.3390/ijerph191610142
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