Cargando…

Terminal Phenoxy Group as a Privileged Moiety of the Drug Scaffold—A Short Review of Most Recent Studies 2013–2022

The terminal phenoxy group is a moiety of many drugs in use today. Numerous literature reports indicated its crucial importance for biological activity; thus, it is a privileged scaffold in medicinal chemistry. This review focuses on the latest achievements in the field of novel potential agents bea...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kozyra, Paweł, Pitucha, Monika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408176/ https://www.ncbi.nlm.nih.gov/pubmed/36012142 http://dx.doi.org/10.3390/ijms23168874

Ejemplares similares

New Potential Agents for Malignant Melanoma Treatment—Most Recent Studies 2020–2022
por: Kozyra, Paweł, et al.
Publicado: (2022)

Newly synthesized peripherally octa-substituted zinc phthalocyanines carrying halogen terminated phenoxy-phenoxy moiety: comparative photochemical and photophysical features
por: KIRBAÇ, Erkan, et al.
Publicado: (2020)

Retention Behavior of Anticancer Thiosemicarbazides in Biomimetic Chromatographic Systems and In Silico Calculations
por: Studziński, Marek, et al.
Publicado: (2023)

Pentacyclic Triterpenoids with Nitrogen-Containing Heterocyclic Moiety, Privileged Hybrids in Anticancer Drug Discovery
por: Khwaza, Vuyolwethu, et al.
Publicado: (2021)

2,4-Dichlorophenoxyacetic Thiosemicarbazides as a New Class of Compounds against Stomach Cancer Potentially Intercalating with DNA †
por: Pitucha, Monika, et al.
Publicado: (2020)

LmrR: A Privileged Scaffold for Artificial Metalloenzymes
por: Roelfes, Gerard
Publicado: (2019)

Indol-3-ylglyoxylamide as Privileged Scaffold in Medicinal Chemistry
por: Barresi, Elisabetta, et al.
Publicado: (2023)

Small Molecules Incorporating Privileged Amidine Moiety as Potential Hits Combating Antibiotic-Resistant Bacteria
por: El-Sayed, Selwan M., et al.
Publicado: (2023)

The Alpha Keto Amide Moiety as a Privileged Motif in Medicinal Chemistry: Current Insights and Emerging Opportunities
por: Robello, Marco, et al.
Publicado: (2021)

Isatin: a privileged scaffold for the design of carbonic anhydrase inhibitors
por: Melis, Claudia, et al.
Publicado: (2016)

Coumarin: A Natural, Privileged and Versatile Scaffold for Bioactive Compounds
por: Stefanachi, Angela, et al.
Publicado: (2018)

The Fellowship of Privileged Scaffolds—One Structure to Inhibit Them All
por: Skoreński, Marcin, et al.
Publicado: (2021)

Pyrroles as Privileged Scaffolds in the Search for New Potential HIV Inhibitors
por: Bianco, Maria da Conceição Avelino Dias, et al.
Publicado: (2021)

An overview of metal-free synthetic routes to isoxazoles: the privileged scaffold
por: Das, Soumyadip, et al.
Publicado: (2021)

An efficient synthesis of 4-phenoxy-quinazoline, 2-phenoxy-quinoxaline, and 2-phenoxy-pyridine derivatives using aryne chemistry
por: Zilla, Mahesh K., et al.
Publicado: (2021)

Privileged Scaffolds for Potent and Specific Inhibitors of Mono-ADP-Ribosylating PARPs
por: Nizi, Maria Giulia, et al.
Publicado: (2023)

Flavonoids and related privileged scaffolds as potential urease inhibitors: a review
por: Al-Rooqi, Munirah M., et al.
Publicado: (2023)

Priviléges /
por: Beauvoir, Simone de, 1908-1986
Publicado: (1955)

Privileges
por: Jagannathan, Mukund
Publicado: (2016)

2-Phenoxyacetohydrazide
por: Fun, Hoong-Kun, et al.
Publicado: (2009)

2-Phenoxypyrimidine
por: Shah Bakhtiar, Nasir, et al.
Publicado: (2008)

Effect of the phenoxy groups on PDIB and its derivatives
por: Song, Peng, et al.
Publicado: (2016)

The Camerino symposium series (1978–2013): a privileged observatory of receptorology development
por: Giannella, Mario, et al.
Publicado: (2013)

Discovery of novel oestrogen receptor α agonists and antagonists by screening a revisited privileged structure moiety for nuclear receptors
por: Masuya, Takahiro, et al.
Publicado: (2019)

5,8-Quinolinedione Scaffold as a Promising Moiety of Bioactive Agents
por: Kadela-Tomanek, Monika, et al.
Publicado: (2019)

Green Synthesis of Privileged Benzimidazole Scaffolds Using Active Deep Eutectic Solvent
por: Di Gioia, Maria Luisa, et al.
Publicado: (2019)

3-Phenylcoumarins as a Privileged Scaffold in Medicinal Chemistry: The Landmarks of the Past Decade
por: Matos, Maria J., et al.
Publicado: (2021)

The privileged immunity of immune privileged organs: the case of the eye
por: Benhar, Inbal, et al.
Publicado: (2012)

The Privilege of Suffering
Publicado: (1886)

The Privilege of Suffering
Publicado: (1886)

Ransomware and Privileges
por: Haber, Morey J.
Publicado: (2020)

Privileged Communications
Publicado: (1852)

Probing In Silico the Benzimidazole Privileged Scaffold for the Development of Drug-like Anti-RSV Agents
por: Cichero, Elena, et al.
Publicado: (2021)

Alternative Benzoxazole Assembly Discovered in Anaerobic Bacteria Provides Access to Privileged Heterocyclic Scaffold
por: Horch, Therese, et al.
Publicado: (2022)

Manipulations of phenylnorbornyl palladium species for multicomponent construction of a bridged polycyclic privileged scaffold
por: Yin, Lina, et al.
Publicado: (2022)

Synthesis and characterization of novel iminobenzoates with terminal pyrazine moieties
por: Ahmad, Mushtaq, et al.
Publicado: (2018)

Novel Natural Product- and Privileged Scaffold-Based Tubulin Inhibitors Targeting the Colchicine Binding Site
por: Dong, Mengqi, et al.
Publicado: (2016)

2,3-Dihydroquinazolin-4(1H)-one as a privileged scaffold in drug design
por: Badolato, Mariateresa, et al.
Publicado: (2018)

Facile and diastereoselective arylation of the privileged 1,4-dihydroisoquinolin-3(2H)-one scaffold
por: Dar’in, Dmitry, et al.
Publicado: (2022)

Aminated Quinolinequinones as Privileged Scaffolds for Antibacterial Agents: Synthesis, In Vitro Evaluation, and Putative Mode of Action
por: Yıldırım, Hatice, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_b1cn8m7dr7kifu4ik7oqrdn7bp