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Adaptation to Hypoxia May Promote Therapeutic Resistance to Androgen Receptor Inhibition in Triple-Negative Breast Cancer

Triple-negative breast cancer (TNBC) surpasses other BC subtypes as the most challenging to treat due to its lack of traditional BC biomarkers. Nearly 30% of TNBC patients express the androgen receptor (AR), and the blockade of androgen production and AR signaling have been the cornerstones of thera...

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Detalles Bibliográficos
Autores principales: Jinna, Nikita, Rida, Padmashree, Smart, Max, LaBarge, Mark, Jovanovic-Talisman, Tijana, Natarajan, Rama, Seewaldt, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408190/
https://www.ncbi.nlm.nih.gov/pubmed/36012111
http://dx.doi.org/10.3390/ijms23168844