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Transcriptome Profile Identifies Actin as an Essential Regulator of Cardiac Myosin Binding Protein C3 Hypertrophic Cardiomyopathy in a Zebrafish Model

Variants in cardiac myosin-binding protein C (cMyBP-C) are the leading cause of inherited hypertrophic cardiomyopathy (HCM), demonstrating the key role that cMyBP-C plays in the heart’s contractile machinery. To investigate the c-MYBPC3 HCM-related cardiac impairment, we generated a zebrafish mypbc3...

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Detalles Bibliográficos
Autores principales:	Da’as, Sahar Isa, Hasan, Waseem, Salem, Rola, Younes, Nadine, Abdelrahman, Doua, Mohamed, Iman A., Aldaalis, Arwa, Temanni, Ramzi, Mathew, Lisa Sara, Lorenz, Stephan, Yacoub, Magdi, Nomikos, Michail, Nasrallah, Gheyath K., Fakhro, Khalid A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408294/ https://www.ncbi.nlm.nih.gov/pubmed/36012114 http://dx.doi.org/10.3390/ijms23168840

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