Differential Impact of Random GC Tetrad Binding and Chromatin Events on Transcriptional Inhibition by Olivomycin A

Olivomycin A (OA), an antibiotic of the aureolic acid family, interferes with gene transcription upon forming complexes with GC-rich regions in the DNA minor groove. We demonstrate that the mechanism of transcriptional deregulation is not limited to OA interaction with GC-containing binding sites fo...

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Detalles Bibliográficos
Autores principales: Isagulieva, Alexandra K., Kaluzhny, Dmitry N., Beniaminov, Artemy D., Soshnikova, Nataliya V., Shtil, Alexander A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408465/
https://www.ncbi.nlm.nih.gov/pubmed/36012127
http://dx.doi.org/10.3390/ijms23168871

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408465/
https://www.ncbi.nlm.nih.gov/pubmed/36012127
http://dx.doi.org/10.3390/ijms23168871

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