Cargando…

Can the Virtual Reality-Based Spatial Memory Test Better Discriminate Mild Cognitive Impairment than Neuropsychological Assessment?

Neuropsychological screening tools for mild cognitive impairment (MCI) have been widely used. However, to date, their sensitivity and specificity still remain unsatisfied. This study aims to investigate whether spatial memory can discriminate MCI better than neuropsychological screening tools. A tot...

Descripción completa

Detalles Bibliográficos
Autor principal: Park, Jin-Hyuck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408476/
https://www.ncbi.nlm.nih.gov/pubmed/36011585
http://dx.doi.org/10.3390/ijerph19169950
_version_ 1784774610435178496
author Park, Jin-Hyuck
author_facet Park, Jin-Hyuck
author_sort Park, Jin-Hyuck
collection PubMed
description Neuropsychological screening tools for mild cognitive impairment (MCI) have been widely used. However, to date, their sensitivity and specificity still remain unsatisfied. This study aims to investigate whether spatial memory can discriminate MCI better than neuropsychological screening tools. A total of 56 healthy older adults and 36 older adults with MCI participated in this study; they performed a spatial cognitive task based on virtual reality (SCT-VR), the Korean version of the Montreal Cognitive Assessment (MoCA-K), and the Wechsler Adult Intelligence Scale-Revised Block Design Test (WAIS-BDT). The discriminant power was compared between the SCT-VR and the MoCA-K, and the reliability and validity of the SCT-VR were analyzed. The spatial memory, assessed by the SCT-VR, showed better sensitivity and specificity (sensitivity: 0.944; specificity: 0.964) than the MoCA-K (sensitivity: 0.857; specificity: 0.746). The test-retest reliability of the SCT-VR was relatively high (ICCs: 0.982, p < 0.001) and the concurrent validity of the SCT-VR with the MoCA-K (r = −0.587, p < 0.001) and the WAIS-BDT (r = −0.594, p < 0.001) was statistically significant. These findings shed light on the importance of spatial memory as a behavioral marker of MCI. The ecologically validated spatial memory tasks based on VR need to be investigated by neuroscientific studies in the future.
format Online
Article
Text
id pubmed-9408476
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-94084762022-08-26 Can the Virtual Reality-Based Spatial Memory Test Better Discriminate Mild Cognitive Impairment than Neuropsychological Assessment? Park, Jin-Hyuck Int J Environ Res Public Health Article Neuropsychological screening tools for mild cognitive impairment (MCI) have been widely used. However, to date, their sensitivity and specificity still remain unsatisfied. This study aims to investigate whether spatial memory can discriminate MCI better than neuropsychological screening tools. A total of 56 healthy older adults and 36 older adults with MCI participated in this study; they performed a spatial cognitive task based on virtual reality (SCT-VR), the Korean version of the Montreal Cognitive Assessment (MoCA-K), and the Wechsler Adult Intelligence Scale-Revised Block Design Test (WAIS-BDT). The discriminant power was compared between the SCT-VR and the MoCA-K, and the reliability and validity of the SCT-VR were analyzed. The spatial memory, assessed by the SCT-VR, showed better sensitivity and specificity (sensitivity: 0.944; specificity: 0.964) than the MoCA-K (sensitivity: 0.857; specificity: 0.746). The test-retest reliability of the SCT-VR was relatively high (ICCs: 0.982, p < 0.001) and the concurrent validity of the SCT-VR with the MoCA-K (r = −0.587, p < 0.001) and the WAIS-BDT (r = −0.594, p < 0.001) was statistically significant. These findings shed light on the importance of spatial memory as a behavioral marker of MCI. The ecologically validated spatial memory tasks based on VR need to be investigated by neuroscientific studies in the future. MDPI 2022-08-12 /pmc/articles/PMC9408476/ /pubmed/36011585 http://dx.doi.org/10.3390/ijerph19169950 Text en © 2022 by the author. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Park, Jin-Hyuck
Can the Virtual Reality-Based Spatial Memory Test Better Discriminate Mild Cognitive Impairment than Neuropsychological Assessment?
title Can the Virtual Reality-Based Spatial Memory Test Better Discriminate Mild Cognitive Impairment than Neuropsychological Assessment?
title_full Can the Virtual Reality-Based Spatial Memory Test Better Discriminate Mild Cognitive Impairment than Neuropsychological Assessment?
title_fullStr Can the Virtual Reality-Based Spatial Memory Test Better Discriminate Mild Cognitive Impairment than Neuropsychological Assessment?
title_full_unstemmed Can the Virtual Reality-Based Spatial Memory Test Better Discriminate Mild Cognitive Impairment than Neuropsychological Assessment?
title_short Can the Virtual Reality-Based Spatial Memory Test Better Discriminate Mild Cognitive Impairment than Neuropsychological Assessment?
title_sort can the virtual reality-based spatial memory test better discriminate mild cognitive impairment than neuropsychological assessment?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408476/
https://www.ncbi.nlm.nih.gov/pubmed/36011585
http://dx.doi.org/10.3390/ijerph19169950
work_keys_str_mv AT parkjinhyuck canthevirtualrealitybasedspatialmemorytestbetterdiscriminatemildcognitiveimpairmentthanneuropsychologicalassessment