Cargando…

A Unique Glassy Cell Carcinoma (GCC) of the Cervix Diagnosed during Pregnancy—A Case Report

Glassy Cell carcinoma (GCC) of the cervix is classified as a unique, aggressive neoplasm, with different sensitivity to chemotherapy and radiotherapy. It is such an extremely rare tumor that it is practically not observed during pregnancy. Information on the coexistence of cervical GCC with pregnanc...

Descripción completa

Detalles Bibliográficos
Autores principales: Grabowska, Marlena, Baum, Ewa, Lewandowska, Małgorzata, Sajdak, Stefan, Dolińska-Kaczmarek, Klaudia, Englert-Golon, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408539/
https://www.ncbi.nlm.nih.gov/pubmed/36011240
http://dx.doi.org/10.3390/healthcare10081583
_version_ 1784774626154381312
author Grabowska, Marlena
Baum, Ewa
Lewandowska, Małgorzata
Sajdak, Stefan
Dolińska-Kaczmarek, Klaudia
Englert-Golon, Monika
author_facet Grabowska, Marlena
Baum, Ewa
Lewandowska, Małgorzata
Sajdak, Stefan
Dolińska-Kaczmarek, Klaudia
Englert-Golon, Monika
author_sort Grabowska, Marlena
collection PubMed
description Glassy Cell carcinoma (GCC) of the cervix is classified as a unique, aggressive neoplasm, with different sensitivity to chemotherapy and radiotherapy. It is such an extremely rare tumor that it is practically not observed during pregnancy. Information on the coexistence of cervical GCC with pregnancy is also unique, so it seems extremely important to disseminate it in order to develop the most effective treatment regimen. Additionally, making any decisions regarding therapeutic methods during pregnancy encounters great ethical problems. We present the case of a 26-year-old pregnant woman, 18 weeks gestation, diagnosed with GCC of the cervix, IB3 grade in the International Federation of Gynecology and Obstetrics (FIGO) scale. Despite the unfavorable prognosis, the use of chemotherapy in a pregnant patient brought on a favorable therapeutic effect, without any negative effects on the fetus. The article also presents a literature review on the epidemiology, pathology, immunohistochemistry, treatment and prognosis of this rare disease.
format Online
Article
Text
id pubmed-9408539
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-94085392022-08-26 A Unique Glassy Cell Carcinoma (GCC) of the Cervix Diagnosed during Pregnancy—A Case Report Grabowska, Marlena Baum, Ewa Lewandowska, Małgorzata Sajdak, Stefan Dolińska-Kaczmarek, Klaudia Englert-Golon, Monika Healthcare (Basel) Case Report Glassy Cell carcinoma (GCC) of the cervix is classified as a unique, aggressive neoplasm, with different sensitivity to chemotherapy and radiotherapy. It is such an extremely rare tumor that it is practically not observed during pregnancy. Information on the coexistence of cervical GCC with pregnancy is also unique, so it seems extremely important to disseminate it in order to develop the most effective treatment regimen. Additionally, making any decisions regarding therapeutic methods during pregnancy encounters great ethical problems. We present the case of a 26-year-old pregnant woman, 18 weeks gestation, diagnosed with GCC of the cervix, IB3 grade in the International Federation of Gynecology and Obstetrics (FIGO) scale. Despite the unfavorable prognosis, the use of chemotherapy in a pregnant patient brought on a favorable therapeutic effect, without any negative effects on the fetus. The article also presents a literature review on the epidemiology, pathology, immunohistochemistry, treatment and prognosis of this rare disease. MDPI 2022-08-21 /pmc/articles/PMC9408539/ /pubmed/36011240 http://dx.doi.org/10.3390/healthcare10081583 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Grabowska, Marlena
Baum, Ewa
Lewandowska, Małgorzata
Sajdak, Stefan
Dolińska-Kaczmarek, Klaudia
Englert-Golon, Monika
A Unique Glassy Cell Carcinoma (GCC) of the Cervix Diagnosed during Pregnancy—A Case Report
title A Unique Glassy Cell Carcinoma (GCC) of the Cervix Diagnosed during Pregnancy—A Case Report
title_full A Unique Glassy Cell Carcinoma (GCC) of the Cervix Diagnosed during Pregnancy—A Case Report
title_fullStr A Unique Glassy Cell Carcinoma (GCC) of the Cervix Diagnosed during Pregnancy—A Case Report
title_full_unstemmed A Unique Glassy Cell Carcinoma (GCC) of the Cervix Diagnosed during Pregnancy—A Case Report
title_short A Unique Glassy Cell Carcinoma (GCC) of the Cervix Diagnosed during Pregnancy—A Case Report
title_sort unique glassy cell carcinoma (gcc) of the cervix diagnosed during pregnancy—a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408539/
https://www.ncbi.nlm.nih.gov/pubmed/36011240
http://dx.doi.org/10.3390/healthcare10081583
work_keys_str_mv AT grabowskamarlena auniqueglassycellcarcinomagccofthecervixdiagnosedduringpregnancyacasereport
AT baumewa auniqueglassycellcarcinomagccofthecervixdiagnosedduringpregnancyacasereport
AT lewandowskamałgorzata auniqueglassycellcarcinomagccofthecervixdiagnosedduringpregnancyacasereport
AT sajdakstefan auniqueglassycellcarcinomagccofthecervixdiagnosedduringpregnancyacasereport
AT dolinskakaczmarekklaudia auniqueglassycellcarcinomagccofthecervixdiagnosedduringpregnancyacasereport
AT englertgolonmonika auniqueglassycellcarcinomagccofthecervixdiagnosedduringpregnancyacasereport
AT grabowskamarlena uniqueglassycellcarcinomagccofthecervixdiagnosedduringpregnancyacasereport
AT baumewa uniqueglassycellcarcinomagccofthecervixdiagnosedduringpregnancyacasereport
AT lewandowskamałgorzata uniqueglassycellcarcinomagccofthecervixdiagnosedduringpregnancyacasereport
AT sajdakstefan uniqueglassycellcarcinomagccofthecervixdiagnosedduringpregnancyacasereport
AT dolinskakaczmarekklaudia uniqueglassycellcarcinomagccofthecervixdiagnosedduringpregnancyacasereport
AT englertgolonmonika uniqueglassycellcarcinomagccofthecervixdiagnosedduringpregnancyacasereport