Cargando…
New Pyrrole Derivatives as Promising Biological Agents: Design, Synthesis, Characterization, In Silico, and Cytotoxicity Evaluation
The current study describes the synthesis, physicochemical characterization and cytotoxicity evaluation of a new series of pyrrole derivatives in order to identify new bioactive molecules. The new pyrroles were obtained by reaction of benzimidazolium bromide derivatives with asymmetrical acetylenes...
Autores principales: | Ivan, Beatrice-Cristina, Barbuceanu, Stefania-Felicia, Hotnog, Camelia Mia, Anghel, Adriana Iuliana, Ancuceanu, Robert Viorel, Mihaila, Mirela Antonela, Brasoveanu, Lorelei Irina, Shova, Sergiu, Draghici, Constantin, Olaru, Octavian Tudorel, Nitulescu, George Mihai, Dinu, Mihaela, Dumitrascu, Florea |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408590/ https://www.ncbi.nlm.nih.gov/pubmed/36012121 http://dx.doi.org/10.3390/ijms23168854 |
Ejemplares similares
-
Synthesis, Characterization and Cytotoxic Evaluation of New Pyrrolo[1,2-b]pyridazines Obtained via Mesoionic Oxazolo-Pyridazinones
por: Ivan, Beatrice-Cristina, et al.
Publicado: (2023) -
Synthesis and Toxicity Evaluation of New Pyrroles Obtained by the Reaction of Activated Alkynes with 1-Methyl-3-(cyanomethyl)benzimidazolium Bromide
por: Ivan, Beatrice-Cristina, et al.
Publicado: (2021) -
Synthesis and Anticancer Evaluation of New 1,3,4-Oxadiazole Derivatives
por: Stecoza, Camelia Elena, et al.
Publicado: (2021) -
New Potential Antitumor Pyrazole Derivatives: Synthesis and Cytotoxic Evaluation
por: Nitulescu, George Mihai, et al.
Publicado: (2013) -
The Importance of the Pyrazole Scaffold in the Design of Protein Kinases Inhibitors as Targeted Anticancer Therapies
por: Nitulescu, George Mihai, et al.
Publicado: (2023)