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Demographic Control Measure Implications of Tuberculosis Infection for Migrant Workers across Taiwan Regions

A sharp increase in migrant workers has raised concerns for TB epidemics, yet optimal TB control strategies remain unclear in Taiwan regions. This study assessed intervention efforts on reducing tuberculosis (TB) infection among migrant workers. We performed large-scale data analyses and used them t...

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Autores principales: Chen, Szu-Chieh, Wang, Tzu-Yun, Tsai, Hsin-Chieh, Chen, Chi-Yun, Lu, Tien-Hsuan, Lin, Yi-Jun, You, Shu-Han, Yang, Ying-Fei, Liao, Chung-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408672/
https://www.ncbi.nlm.nih.gov/pubmed/36011542
http://dx.doi.org/10.3390/ijerph19169899
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author Chen, Szu-Chieh
Wang, Tzu-Yun
Tsai, Hsin-Chieh
Chen, Chi-Yun
Lu, Tien-Hsuan
Lin, Yi-Jun
You, Shu-Han
Yang, Ying-Fei
Liao, Chung-Min
author_facet Chen, Szu-Chieh
Wang, Tzu-Yun
Tsai, Hsin-Chieh
Chen, Chi-Yun
Lu, Tien-Hsuan
Lin, Yi-Jun
You, Shu-Han
Yang, Ying-Fei
Liao, Chung-Min
author_sort Chen, Szu-Chieh
collection PubMed
description A sharp increase in migrant workers has raised concerns for TB epidemics, yet optimal TB control strategies remain unclear in Taiwan regions. This study assessed intervention efforts on reducing tuberculosis (TB) infection among migrant workers. We performed large-scale data analyses and used them to develop a control-based migrant worker-associated susceptible–latently infected–infectious–recovered (SLTR) model. We used the SLTR model to assess potential intervention strategies such as social distancing, early screening, and directly observed treatment, short-course (DOTS) for TB transmission among migrant workers and locals in three major hotspot cities from 2018 to 2023. We showed that social distancing was the best single strategy, while the best dual measure was social distancing coupled with early screening. However, the effectiveness of the triple strategy was marginally (1–3%) better than that of the dual measure. Our study provides a mechanistic framework to facilitate understanding of TB transmission dynamics between locals and migrant workers and to recommend better prevention strategies in anticipation of achieving WHO’s milestones by the next decade. Our work has implications for migrant worker-associated TB infection prevention on a global scale and provides a knowledge base for exploring how outcomes can be best implemented by alternative control measure approaches.
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spelling pubmed-94086722022-08-26 Demographic Control Measure Implications of Tuberculosis Infection for Migrant Workers across Taiwan Regions Chen, Szu-Chieh Wang, Tzu-Yun Tsai, Hsin-Chieh Chen, Chi-Yun Lu, Tien-Hsuan Lin, Yi-Jun You, Shu-Han Yang, Ying-Fei Liao, Chung-Min Int J Environ Res Public Health Article A sharp increase in migrant workers has raised concerns for TB epidemics, yet optimal TB control strategies remain unclear in Taiwan regions. This study assessed intervention efforts on reducing tuberculosis (TB) infection among migrant workers. We performed large-scale data analyses and used them to develop a control-based migrant worker-associated susceptible–latently infected–infectious–recovered (SLTR) model. We used the SLTR model to assess potential intervention strategies such as social distancing, early screening, and directly observed treatment, short-course (DOTS) for TB transmission among migrant workers and locals in three major hotspot cities from 2018 to 2023. We showed that social distancing was the best single strategy, while the best dual measure was social distancing coupled with early screening. However, the effectiveness of the triple strategy was marginally (1–3%) better than that of the dual measure. Our study provides a mechanistic framework to facilitate understanding of TB transmission dynamics between locals and migrant workers and to recommend better prevention strategies in anticipation of achieving WHO’s milestones by the next decade. Our work has implications for migrant worker-associated TB infection prevention on a global scale and provides a knowledge base for exploring how outcomes can be best implemented by alternative control measure approaches. MDPI 2022-08-11 /pmc/articles/PMC9408672/ /pubmed/36011542 http://dx.doi.org/10.3390/ijerph19169899 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Chen, Szu-Chieh
Wang, Tzu-Yun
Tsai, Hsin-Chieh
Chen, Chi-Yun
Lu, Tien-Hsuan
Lin, Yi-Jun
You, Shu-Han
Yang, Ying-Fei
Liao, Chung-Min
Demographic Control Measure Implications of Tuberculosis Infection for Migrant Workers across Taiwan Regions
title Demographic Control Measure Implications of Tuberculosis Infection for Migrant Workers across Taiwan Regions
title_full Demographic Control Measure Implications of Tuberculosis Infection for Migrant Workers across Taiwan Regions
title_fullStr Demographic Control Measure Implications of Tuberculosis Infection for Migrant Workers across Taiwan Regions
title_full_unstemmed Demographic Control Measure Implications of Tuberculosis Infection for Migrant Workers across Taiwan Regions
title_short Demographic Control Measure Implications of Tuberculosis Infection for Migrant Workers across Taiwan Regions
title_sort demographic control measure implications of tuberculosis infection for migrant workers across taiwan regions
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408672/
https://www.ncbi.nlm.nih.gov/pubmed/36011542
http://dx.doi.org/10.3390/ijerph19169899
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