Cargando…

Monitoring Anti-PEG Antibodies Level upon Repeated Lipid Nanoparticle-Based COVID-19 Vaccine Administration

PEGylated lipids are one of the four constituents of lipid nanoparticle mRNA COVID-19 vaccines. Therefore, various concerns have been raised on the generation of anti-PEG antibodies and their potential role in inducing hypersensitivity reactions following vaccination or in reducing vaccine efficacy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guerrini, Giuditta, Gioria, Sabrina, Sauer, Aisha V., Lucchesi, Simone, Montagnani, Francesca, Pastore, Gabiria, Ciabattini, Annalisa, Medaglini, Donata, Calzolai, Luigi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408675/ https://www.ncbi.nlm.nih.gov/pubmed/36012103 http://dx.doi.org/10.3390/ijms23168838

Ejemplares similares

Physicochemical Characterization Cascade of Nanoadjuvant–Antigen Systems for Improving Vaccines
por: Guerrini, Giuditta, et al.
Publicado: (2021)

Short or Long Interval between Priming and Boosting: Does It Impact on the Vaccine Immunogenicity?
por: Pettini, Elena, et al.
Publicado: (2021)

A third dose of mRNA-1273 vaccine improves SARS-CoV-2 immunity in HCT recipients with low antibody response after 2 doses
por: Pettini, Elena, et al.
Publicado: (2022)

Computational Analysis of Multiparametric Flow Cytometric Data to Dissect B Cell Subsets in Vaccine Studies
por: Lucchesi, Simone, et al.
Publicado: (2019)

Does Nirmatrelvir/Ritonavir Influence the Immune Response against SARS-CoV-2, Independently from Rebound?
por: Panza, Francesca, et al.
Publicado: (2023)

Optimized Protocol for the Detection of Multifunctional Epitope-Specific CD4(+) T Cells Combining MHC-II Tetramer and Intracellular Cytokine Staining Technologies
por: Pastore, Gabiria, et al.
Publicado: (2019)

Modulation of Primary Immune Response by Different Vaccine Adjuvants
por: Ciabattini, Annalisa, et al.
Publicado: (2016)

Evidence of SARS-CoV-2-Specific Memory B Cells Six Months After Vaccination With the BNT162b2 mRNA Vaccine
por: Ciabattini, Annalisa, et al.
Publicado: (2021)

Trajectory of Spike-Specific B Cells Elicited by Two Doses of BNT162b2 mRNA Vaccine
por: Ciabattini, Annalisa, et al.
Publicado: (2023)

Heterologous Prime-Boost Combinations Highlight the Crucial Role of Adjuvant in Priming the Immune System
por: Ciabattini, Annalisa, et al.
Publicado: (2018)

From Bivariate to Multivariate Analysis of Cytometric Data: Overview of Computational Methods and Their Application in Vaccination Studies
por: Lucchesi, Simone, et al.
Publicado: (2020)

B cell response after SARS-CoV-2 mRNA vaccination in people living with HIV
por: Polvere, Jacopo, et al.
Publicado: (2023)

The third dose of mRNA SARS-CoV-2 vaccines enhances the spike-specific antibody and memory B cell response in myelofibrosis patients
por: Fiorino, Fabio, et al.
Publicado: (2022)

The Slower Antibody Response in Myelofibrosis Patients after Two Doses of mRNA SARS-CoV-2 Vaccine Calls for a Third Dose
por: Fiorino, Fabio, et al.
Publicado: (2021)

CD4(+) T Cell Priming as Biomarker to Study Immune Response to Preventive Vaccines
por: Ciabattini, Annalisa, et al.
Publicado: (2013)

Profiling the B cell immune response elicited by vaccination against the respiratory virus SARS-CoV-2
por: Pettini, Elena, et al.
Publicado: (2022)

Role of the Microbiota in the Modulation of Vaccine Immune Responses
por: Ciabattini, Annalisa, et al.
Publicado: (2019)

Analytical Ultracentrifugation Detects Quaternary Rearrangements and Antibody-Induced Conformational Selection of the SARS-CoV-2 Spike Trimer
por: Guerrini, Giuditta, et al.
Publicado: (2023)

Prime-Boost Strategies in Mucosal Immunization Affect Local IgA Production and the Type of Th Response
por: Fiorino, Fabio, et al.
Publicado: (2013)

Distribution of Primed T Cells and Antigen-Loaded Antigen Presenting Cells Following Intranasal Immunization in Mice
por: Ciabattini, Annalisa, et al.
Publicado: (2011)

Characterization of the Antigen-Specific CD4(+) T Cell Response Induced by Prime-Boost Strategies with CAF01 and CpG Adjuvants Administered by the Intranasal and Subcutaneous Routes
por: Ciabattini, Annalisa, et al.
Publicado: (2015)

Shelter from the cytokine storm: pitfalls and prospects in the development of SARS-CoV-2 vaccines for an elderly population
por: Ciabattini, Annalisa, et al.
Publicado: (2020)

Long-Term Anti-Bacterial Immunity against Systemic Infection by Salmonella enterica Serovar Typhimurium Elicited by a GMMA-Based Vaccine
por: Fiorino, Fabio, et al.
Publicado: (2021)

Vaginal Immunization to Elicit Primary T-Cell Activation and Dissemination
por: Pettini, Elena, et al.
Publicado: (2013)

Using IFN-gamma release assay to confirm tuberculin skin test improves the screening of latent tuberculosis infection in Italian healthcare workers
por: Olivieri, Raffaela, et al.
Publicado: (2016)

Transcriptomics of the Vaccine Immune Response: Priming With Adjuvant Modulates Recall Innate Responses After Boosting
por: Santoro, Francesco, et al.
Publicado: (2018)

Impact of Viral Decontamination Method on Cytokine Profile of COVID-19 Patients
por: Magrì, Davide, et al.
Publicado: (2021)

Differences in Physico-Chemical Properties and Immunological Response in Nanosimilar Complex Drugs: The Case of Liposomal Doxorubicin
por: Lipsa, Dorelia, et al.
Publicado: (2023)

Editorial: Advanced Immunization Technologies for Next Generation Vaccines
por: Medaglini, Donata, et al.
Publicado: (2020)

Recombinant Haemagglutinin Derived From the Ciliated Protozoan Tetrahymena thermophila Is Protective Against Influenza Infection
por: Jawinski, Karina, et al.
Publicado: (2019)

Human neutralizing antibodies to cold linear epitopes and to subdomain 1 of SARS-CoV-2
por: Bianchini, Filippo, et al.
Publicado: (2022)

Human neutralizing antibodies to cold linear epitopes and subdomain 1 of the SARS-CoV-2 spike glycoprotein
por: Bianchini, Filippo, et al.
Publicado: (2023)

A Stochastic Model for CD4+ T Cell Proliferation and Dissemination Network in Primary Immune Response
por: Boianelli, Alessandro, et al.
Publicado: (2015)

PEG-OligoRNA Hybridization of mRNA for Developing Sterically Stable Lipid Nanoparticles toward In Vivo Administration
por: Kurimoto, Shota, et al.
Publicado: (2019)

Doxorubicin-Loaded PEG-PCL-PEG Micelle Using Xenograft Model of Nude Mice: Effect of Multiple Administration of Micelle on the Suppression of Human Breast Cancer
por: Cuong, Nguyen-Van, et al.
Publicado: (2010)

Modulating charge-dependent and folding-mediated antimicrobial interactions at peptide–lipid interfaces
por: Iavicoli, Patrizia, et al.
Publicado: (2016)

Interferon-γ from Brain Leukocytes Enhances Meningitis by Type 4 Streptococcus pneumoniae
por: Pettini, Elena, et al.
Publicado: (2015)

The SARS-CoV-2 Nucleoprotein Induces Innate Memory in Human Monocytes
por: Urbán, Patricia, et al.
Publicado: (2022)

The Peg Formboards
por: Wallin, J. E. Wallace
Publicado: (1918)

Pegging Away
Publicado: (1892)

Cannot write session to /tmp/vufind_sessions/sess_3joi7f3mk567fl7ghe6lqkj1gq