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Systolic Blood Pressure Trajectories and the Progression of Arterial Stiffness in Chinese Adults

Evidence on the association between systolic blood pressure (SBP) trajectories and arterial stiffness progression is scarce. The current study aimed to identify the association between SBP trajectories and the progression of arterial stiffness over time in Chinese adults. This study included 30,384...

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Autores principales: Liu, Run, Li, Dankang, Yang, Yingping, Hu, Yonghua, Wu, Shouling, Tian, Yaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408732/
https://www.ncbi.nlm.nih.gov/pubmed/36011682
http://dx.doi.org/10.3390/ijerph191610046
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author Liu, Run
Li, Dankang
Yang, Yingping
Hu, Yonghua
Wu, Shouling
Tian, Yaohua
author_facet Liu, Run
Li, Dankang
Yang, Yingping
Hu, Yonghua
Wu, Shouling
Tian, Yaohua
author_sort Liu, Run
collection PubMed
description Evidence on the association between systolic blood pressure (SBP) trajectories and arterial stiffness progression is scarce. The current study aimed to identify the association between SBP trajectories and the progression of arterial stiffness over time in Chinese adults. This study included 30,384 adult participants. Latent mixture modeling was used to identify the SBP trajectory patterns from 2006 to 2010. The brachial–ankle pulse wave velocity (baPWV) was used to measure arterial stiffness. The associations between SBP trajectories and the progression of arterial stiffness were explored using multiple linear regression models. We identified five distinct SBP trajectories and took the low-stable group as the reference. In the cross-sectional analysis, the four SBP trajectories were significantly associated with higher baPWV levels (p < 0.001) compared with the reference. In the longitudinal analysis, after adjusting for covariates and the baseline baPWV, the SBP trajectories were significantly associated with the progression of the baPWV, with corresponding β (95% CI) values of 23.3 (17.2–29.5) cm/s per year for the moderate-stable group, 44.8 (36.6–52.9) cm/s per year for the moderate-increasing group, 54.6 (42.2–67.0) cm/s per year for the elevated-decreasing group, and 66.8 (54.7–79.0) cm/s per year for the elevated-stable group. Similar significant results were also observed in the non-hypertensive population. In conclusion, SBP trajectories were related to the baseline baPWV and the progression of the baPWV. Blood pressure control may be considered a therapeutic target to further reduce the risk of arterial stiffness.
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spelling pubmed-94087322022-08-26 Systolic Blood Pressure Trajectories and the Progression of Arterial Stiffness in Chinese Adults Liu, Run Li, Dankang Yang, Yingping Hu, Yonghua Wu, Shouling Tian, Yaohua Int J Environ Res Public Health Article Evidence on the association between systolic blood pressure (SBP) trajectories and arterial stiffness progression is scarce. The current study aimed to identify the association between SBP trajectories and the progression of arterial stiffness over time in Chinese adults. This study included 30,384 adult participants. Latent mixture modeling was used to identify the SBP trajectory patterns from 2006 to 2010. The brachial–ankle pulse wave velocity (baPWV) was used to measure arterial stiffness. The associations between SBP trajectories and the progression of arterial stiffness were explored using multiple linear regression models. We identified five distinct SBP trajectories and took the low-stable group as the reference. In the cross-sectional analysis, the four SBP trajectories were significantly associated with higher baPWV levels (p < 0.001) compared with the reference. In the longitudinal analysis, after adjusting for covariates and the baseline baPWV, the SBP trajectories were significantly associated with the progression of the baPWV, with corresponding β (95% CI) values of 23.3 (17.2–29.5) cm/s per year for the moderate-stable group, 44.8 (36.6–52.9) cm/s per year for the moderate-increasing group, 54.6 (42.2–67.0) cm/s per year for the elevated-decreasing group, and 66.8 (54.7–79.0) cm/s per year for the elevated-stable group. Similar significant results were also observed in the non-hypertensive population. In conclusion, SBP trajectories were related to the baseline baPWV and the progression of the baPWV. Blood pressure control may be considered a therapeutic target to further reduce the risk of arterial stiffness. MDPI 2022-08-15 /pmc/articles/PMC9408732/ /pubmed/36011682 http://dx.doi.org/10.3390/ijerph191610046 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Liu, Run
Li, Dankang
Yang, Yingping
Hu, Yonghua
Wu, Shouling
Tian, Yaohua
Systolic Blood Pressure Trajectories and the Progression of Arterial Stiffness in Chinese Adults
title Systolic Blood Pressure Trajectories and the Progression of Arterial Stiffness in Chinese Adults
title_full Systolic Blood Pressure Trajectories and the Progression of Arterial Stiffness in Chinese Adults
title_fullStr Systolic Blood Pressure Trajectories and the Progression of Arterial Stiffness in Chinese Adults
title_full_unstemmed Systolic Blood Pressure Trajectories and the Progression of Arterial Stiffness in Chinese Adults
title_short Systolic Blood Pressure Trajectories and the Progression of Arterial Stiffness in Chinese Adults
title_sort systolic blood pressure trajectories and the progression of arterial stiffness in chinese adults
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408732/
https://www.ncbi.nlm.nih.gov/pubmed/36011682
http://dx.doi.org/10.3390/ijerph191610046
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