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NX210c Peptide Promotes Glutamatergic Receptor-Mediated Synaptic Transmission and Signaling in the Mouse Central Nervous System

NX210c is a disease-modifying dodecapeptide derived from the subcommissural organ-spondin that is under preclinical and clinical development for the treatment of neurological disorders. Here, using whole-cell patch-clamp recordings, we demonstrate that NX210c increased α-amino-3-hydroxy-5-methyl-4-i...

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Detalles Bibliográficos
Autores principales: Lemarchant, Sighild, Sourioux, Mélissa, Le Douce, Juliette, Henriques, Alexandre, Callizot, Noëlle, Hugues, Sandrine, Farinelli, Mélissa, Godfrin, Yann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408760/
https://www.ncbi.nlm.nih.gov/pubmed/36012124
http://dx.doi.org/10.3390/ijms23168867