Cargando…
Chaperone-Mediated Autophagy in Pericytes: A Key Target for the Development of New Treatments against Glioblastoma Progression
Glioblastoma (GB) cells physically interact with peritumoral pericytes (PCs) present in the brain microvasculature. These interactions facilitate tumor cells to aberrantly increase and benefit from chaperone-mediated autophagy (CMA) in the PC. GB-induced CMA leads to major changes in PC immunomodula...
Autores principales: | Salinas, María Dolores, Valdor, Rut |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408771/ https://www.ncbi.nlm.nih.gov/pubmed/36012149 http://dx.doi.org/10.3390/ijms23168886 |
Ejemplares similares
-
Chaperone-Mediated Autophagy Ablation in Pericytes Reveals New Glioblastoma Prognostic Markers and Efficient Treatment Against Tumor Progression
por: Molina, María Luisa, et al.
Publicado: (2022) -
Glioblastoma ablates pericytes antitumor immune function through aberrant up-regulation of chaperone-mediated autophagy
por: Valdor, Rut, et al.
Publicado: (2019) -
Glioblastoma progression is assisted by induction of immunosuppressive function of pericytes through interaction with tumor cells
por: Valdor, Rut, et al.
Publicado: (2017) -
Autophagy in the Immunosuppressive Perivascular Microenvironment of Glioblastoma
por: Molina, Maria L., et al.
Publicado: (2019) -
Chaperone mediated autophagy regulates T cell responses through targeted degradation of negative regulators of T cell activation
por: Valdor, Rut, et al.
Publicado: (2014)