Cargando…

Optimized Apamin-Mediated Nano-Lipidic Carrier Potentially Enhances the Cytotoxicity of Ellagic Acid against Human Breast Cancer Cells

Ellagic acid has recently attracted increasing attention regarding its role in the prevention and treatment of cancer. Surface functionalized nanocarriers have been recently studied for enhancing cancer cells’ penetration and achieving better tumor-targeted delivery of active ingredients. Therefore,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Badr-Eldin, Shaimaa M., Aldawsari, Hibah M., Fahmy, Usama A., Ahmed, Osama A. A., Alhakamy, Nabil A., Al-hejaili, Omar D., Alhassan, Alhanoof A., Ammari, Ghadeer A., Alhazmi, Shouq I., Alawadi, Raghad M., Bakhaidar, Rana, Alamoudi, Abdulmohsen J., Neamatallah, Thikryat, Tima, Singkome
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408819/ https://www.ncbi.nlm.nih.gov/pubmed/36012704 http://dx.doi.org/10.3390/ijms23169440

Ejemplares similares

Merging Experimental Design and Nanotechnology for the Development of Optimized Simvastatin Spanlastics: A Promising Combined Strategy for Augmenting the Suppression of Various Human Cancer Cells
por: Badr-Eldin, Shaimaa M., et al.
Publicado: (2022)

Lipidic Nano-Sized Emulsomes Potentiates the Cytotoxic and Apoptotic Effects of Raloxifene Hydrochloride in MCF-7 Human Breast Cancer Cells: Factorial Analysis and In Vitro Anti-Tumor Activity Assessment
por: Aldawsari, Hibah M., et al.
Publicado: (2021)

Novel Nanoconjugate of Apamin and Ceftriaxone for Management of Diabetic Wounds
por: Alamoudi, Abdullah A., et al.
Publicado: (2022)

Green Nanoemulsion Stabilized by In Situ Self-Assembled Natural Oil/Native Cyclodextrin Complexes: An Eco-Friendly Approach for Enhancing Anticancer Activity of Costunolide against Lung Cancer Cells
por: Alhakamy, Nabil A., et al.
Publicado: (2022)

Apamin-Conjugated Alendronate Sodium Nanocomplex for Management of Pancreatic Cancer
por: Alhakamy, Nabil A., et al.
Publicado: (2021)

Optimized 2-methoxyestradiol invasomes fortified with apamin: a promising approach for suppression of A549 lung cancer cells
por: Awan, Zuhier A., et al.
Publicado: (2022)

Intranasal Niosomal In Situ Gel as a Promising Approach for Enhancing Flibanserin Bioavailability and Brain Delivery: In Vitro Optimization and Ex Vivo/In Vivo Evaluation
por: Fahmy, Usama A., et al.
Publicado: (2020)

Development of an Icariin-Loaded Bilosome-Melittin Formulation with Improved Anticancer Activity against Cancerous Pancreatic Cells
por: Alhakamy, Nabil A., et al.
Publicado: (2021)

Optimized Ellagic Acid–Ca Pectinate Floating Beads for Gastroprotection against Indomethacin-Induced Gastric Injury in Rats
por: Alhakamy, Nabil A., et al.
Publicado: (2020)

Apamin structure and pharmacology revisited
por: Kuzmenkov, Alexey I., et al.
Publicado: (2022)

Gum Acacia Functionalized Colloidal Gold Nanoparticles of Letrozole as Biocompatible Drug Delivery Carrier for Treatment of Breast Cancer
por: Aldawsari, Hibah M., et al.
Publicado: (2021)

Pumpkin Oil–Based Nanostructured Lipid Carrier System for Antiulcer Effect in NSAID-Induced Gastric Ulcer Model in Rats
por: Ahmed, Osama A A, et al.
Publicado: (2020)

Effects of the CB1 Receptor Antagonists AM6545 and AM4113 on Insulin Resistance in a High-Fructose High-Salt Rat Model of Metabolic Syndrome
por: Eid, Basma G., et al.
Publicado: (2020)

Nano Ellagic Acid Counteracts Cisplatin-Induced Upregulation in OAT1 and OAT3: A Possible Nephroprotection Mechanism
por: Neamatallah, Thikryat, et al.
Publicado: (2020)

Adenosine Conjugated Docetaxel Nanoparticles—Proof of Concept Studies for Non-Small Cell Lung Cancer
por: Aldawsari, Hibah M., et al.
Publicado: (2022)

Omeprazole Prevents Colistin-Induced Nephrotoxicity in Rats: Emphasis on Oxidative Stress, Inflammation, Apoptosis and Colistin Accumulation in Kidneys
por: Nasrullah, Mohammed Z., et al.
Publicado: (2022)

Correction: Neamatallah et al. Nano Ellagic Acid Counteracts Cisplatin-Induced Upregulation in OAT1 and OAT3: A Possible Nephroprotection Mechanism. Molecules 2020, 25, 3031
por: Neamatallah, Thikryat, et al.
Publicado: (2023)

Effects of the CB1 receptor antagonists AM6545 and AM4113 on metabolic syndrome-induced prostatic hyperplasia in rats
por: Eid, Basma G, et al.
Publicado: (2023)

Mitogen-Activated Protein Kinase Pathway: A Critical Regulator in Tumor-associated Macrophage Polarization
por: Neamatallah, Thikryat
Publicado: (2019)

Delayed inflammatory reaction to hyaluronic acid lip filler after the Pfizer-BioNTech COVID-19 vaccine: A case report
por: Neamatallah, Thikryat
Publicado: (2023)

Updates on Molecular and Biochemical Development and Progression of Prostate Cancer
por: Fahmy, Omar, et al.
Publicado: (2021)

Amiodarone Inhibits Apamin-Sensitive Potassium Currents
por: Turker, Isik, et al.
Publicado: (2013)

Scorpion Venom-Functionalized Quercetin Phytosomes for Breast Cancer Management: In Vitro Response Surface Optimization and Anticancer Activity against MCF-7 Cells
por: Alhakamy, Nabil A., et al.
Publicado: (2021)

Neuroprotective and Antioxidant Effect of Naringenin-Loaded Nanoparticles for Nose-to-Brain Delivery
por: Md, Shadab, et al.
Publicado: (2019)

Phyto-Phospholipid Conjugated Scorpion Venom Nanovesicles as Promising Carrier That Improves Efficacy of Thymoquinone against Adenocarcinoma Human Alveolar Basal Epithelial Cells
por: Asfour, Hani Z., et al.
Publicado: (2021)

Anticonvulsant and Neuroprotective Activities of Phragmanthera austroarabica Extract in Pentylenetetrazole-Kindled Mice
por: Aldawsari, Hibah M., et al.
Publicado: (2017)

Anti-angiogenic agents for the treatment of solid tumors: Potential pathways, therapy and current strategies – A review
por: Al-Abd, Ahmed M., et al.
Publicado: (2017)

Interference with TGFβ1-Mediated Inflammation and Fibrosis Underlies Reno-Protective Effects of the CB1 Receptor Neutral Antagonists AM6545 and AM4113 in a Rat Model of Metabolic Syndrome
por: Eid, Basma G., et al.
Publicado: (2021)

Encapsulation of Lovastatin in Zein Nanoparticles Exhibits Enhanced Apoptotic Activity in HepG2 Cells
por: Alhakamy, Nabil A., et al.
Publicado: (2019)

Optimized Self-Nanoemulsifying Delivery System Based on Plant-Derived Oil Augments Alpha-Lipoic Acid Protective Effects Against Experimentally Induced Gastric Lesions
por: Badr-Eldin, Shaimaa M., et al.
Publicado: (2021)

Protective Effects of Apamin on Acetaminophen-Induced Hepatotoxicity in Mice
por: Jang, Hyo-Jeong, et al.
Publicado: (2023)

Wasp venom peptide improves the proapoptotic activity of alendronate sodium in A549 lung cancer cells
por: Alhakamy, Nabil A., et al.
Publicado: (2022)

Formulation Design, Statistical Optimization, and In Vitro Evaluation of a Naringenin Nanoemulsion to Enhance Apoptotic Activity in A549 Lung Cancer Cells
por: Md, Shadab, et al.
Publicado: (2020)

Chitosan-Based Microparticles Enhance Ellagic Acid’s Colon Targeting and Proapoptotic Activity
por: Alhakamy, Nabil A., et al.
Publicado: (2020)

The Encapsulation of Febuxostat into Emulsomes Strongly Enhances the Cytotoxic Potential of the Drug on HCT 116 Colon Cancer Cells
por: Fahmy, Usama A., et al.
Publicado: (2020)

Evaluation of the Antiviral Activity of Sitagliptin-Glatiramer Acetate Nano-Conjugates against SARS-CoV-2 Virus
por: Alhakamy, Nabil A., et al.
Publicado: (2021)

The Protective Effect of Apamin on LPS/Fat-Induced Atherosclerotic Mice
por: Kim, Soo-Jung, et al.
Publicado: (2012)

Apamin suppresses biliary fibrosis and activation of hepatic stellate cells
por: Kim, Jung-Yeon, et al.
Publicado: (2017)

Formulation and Optimization of Avanafil Biodegradable Polymeric Nanoparticles: A Single-Dose Clinical Pharmacokinetic Evaluation
por: Aldawsari, Hibah M., et al.
Publicado: (2020)

Heterogeneous Upregulation of Apamin‐Sensitive Potassium Currents in Failing Human Ventricles
por: Chang, Po‐Cheng, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_719k8v7bm8i165pnunonbac993