Cargando…

The Function of N-Myc Downstream-Regulated Gene 2 (NDRG2) as a Negative Regulator in Tumor Cell Metastasis

N-myc downstream-regulated gene 2 (NDRG2) is a tumor-suppressor gene that suppresses tumorigenesis and metastasis of tumors and increases sensitivity to anti-cancer drugs. In this review, we summarize information on the clinicopathological characteristics of tumor patients according to NDRG2 express...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Ki Won, Lim, Seyeon, Kim, Kwang Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408851/ https://www.ncbi.nlm.nih.gov/pubmed/36012631 http://dx.doi.org/10.3390/ijms23169365

Ejemplares similares

N-myc Downstream-Regulated Gene 2 (NDRG2) Function as a Positive Regulator of Apoptosis: A New Insight into NDRG2 as a Tumor Suppressor
por: Kim, Gayeon, et al.
Publicado: (2021)

Emerging role of N-myc downstream-regulated gene 2 (NDRG2) in cancer
por: Hu, Wei, et al.
Publicado: (2015)

N-myc downstream-regulated gene 2 (NDRG2) promoter methylation and expression in pituitary adenoma
por: Vaitkiene, Paulina, et al.
Publicado: (2017)

A Tumor Suppressor Gene, N-myc Downstream-Regulated Gene 1 (NDRG1), in Gliomas and Glioblastomas
por: Nakahara, Yukiko, et al.
Publicado: (2022)

Expression profile of the N-myc Downstream Regulated Gene 2 (NDRG2) in human cancers with focus on breast cancer
por: Lorentzen, Anders, et al.
Publicado: (2011)

Structural and Biophysical Analyses of Human N-Myc Downstream-Regulated Gene 3 (NDRG3) Protein
por: Kim, Kyung Rok, et al.
Publicado: (2020)

Overexpression of N-Myc Downstream-Regulated Gene 2 (NDRG2) Regulates the Proliferation and Invasion of Bladder Cancer Cells In Vitro and In Vivo
por: Li, Ruixiao, et al.
Publicado: (2013)

A Deletion in the N-Myc Downstream Regulated Gene 1 (NDRG1) Gene in Greyhounds with Polyneuropathy
por: Drögemüller, Cord, et al.
Publicado: (2010)

N-myc downstream regulated gene 1 (ndrg1) functions as a molecular switch for cellular adaptation to hypoxia
por: Park, Jong S, et al.
Publicado: (2022)

mTOR Regulation of N-Myc Downstream Regulated 1 (NDRG1) Phosphorylation in Clear Cell Renal Cell Carcinoma
por: Valluri, Anisha, et al.
Publicado: (2023)

N-myc Downstream Regulated Gene 1 (NDRG1) Promotes Metastasis of Human Scirrhous Gastric Cancer Cells through Epithelial Mesenchymal Transition
por: Ureshino, Hiroki, et al.
Publicado: (2012)

A Gly98Val Mutation in the N-Myc Downstream Regulated Gene 1 (NDRG1) in Alaskan Malamutes with Polyneuropathy
por: Bruun, Camilla S., et al.
Publicado: (2013)

The iron chelator Dp44mT inhibits hepatocellular carcinoma metastasis via N-Myc downstream-regulated gene 2 (NDRG2)/gp130/STAT3 pathway
por: Wang, Jiabei, et al.
Publicado: (2014)

N-myc Downstream-Regulated Gene 1 (NDRG1) Regulates Vascular Endothelial Growth Factor A (VEGFA) and Malignancies in Glioblastoma Multiforme (GBM)
por: Zhang, Xufan, et al.
Publicado: (2022)

Retracted: N-myc Downstream-Regulated Gene 1 (NDRG1) Regulates Vascular Endothelial Growth Factor A (VEGFA) and Malignancies in Glioblastoma Multiforme (GBM)
por: International, BioMed Research
Publicado: (2023)

N-MYC Downstream Regulated Gene 4 (NDRG4), a Frequent Downregulated Gene through DNA Hypermethylation, plays a Tumor Suppressive Role in Esophageal Adenocarcinoma
por: Cao, Longlong, et al.
Publicado: (2020)

N-myc downstream regulated gene 1 inhibition of tumor progression in Caco2 cells
por: He, Yi-Xiao, et al.
Publicado: (2022)

Overexpressed MicroRNA-182 Promotes Proliferation and Invasion in Prostate Cancer PC-3 Cells by Down-Regulating N-myc Downstream Regulated Gene 1 (NDRG1)
por: Liu, Ranlu, et al.
Publicado: (2013)

N-myc Downstream Regulated 1 (NDRG1) Is Regulated by Eukaryotic Initiation Factor 3a (eIF3a) during Cellular Stress Caused by Iron Depletion
por: Lane, Darius J. R., et al.
Publicado: (2013)

Intelectin 1 suppresses the growth, invasion and metastasis of neuroblastoma cells through up-regulation of N-myc downstream regulated gene 2
por: Li, Dan, et al.
Publicado: (2015)

N-Myc downstream-regulated gene 2 is involved in p53-mediated apoptosis
por: Liu, Na, et al.
Publicado: (2008)

Reduced expression of N-Myc downstream-regulated gene 2 in human thyroid cancer
por: Zhao, Huadong, et al.
Publicado: (2008)

Crystal Structure of the Human N-Myc Downstream-regulated Gene 2 Protein Provides Insight into Its Role as a Tumor Suppressor
por: Hwang, Jungwon, et al.
Publicado: (2011)

Correction: N-myc Downstream Regulated 1 (NDRG1) Is Regulated by Eukaryotic Initiation Factor 3a (eIF3a) during Cellular Stress Caused by Iron Depletion
por: Lane, Darius J. R., et al.
Publicado: (2016)

Differential expression and hypoxia‐mediated regulation of the N‐myc downstream regulated gene family
por: Le, Nguyet, et al.
Publicado: (2021)

The Metastasis Suppressor, N-myc Downregulated Gene 1 (NDRG1), Is a Prognostic Biomarker for Human Colorectal Cancer
por: Mao, Zhihai, et al.
Publicado: (2013)

N-myc downstream regulated gene 1 modulates Wnt-β-catenin signalling and pleiotropically suppresses metastasis
por: Liu, Wen, et al.
Publicado: (2012)

The Expression and Localization of N-Myc Downstream-Regulated Gene 1 in Human Trophoblasts
por: Shi, Xiao-Hua, et al.
Publicado: (2013)

Expression and Significance of N-myc downstream regulated gene 2 in the process of Esophageal Squamous Cell Carcinogenesis
por: Feng, Rui-Bing, et al.
Publicado: (2022)

NDRG2 Sensitizes Myeloid Leukemia to Arsenic Trioxide via GSK3β–NDRG2–PP2A Complex Formation
por: Park, Soojong, et al.
Publicado: (2019)

Pathophysiological significance of N‐myc downstream‐regulated gene 2 in cancer development through protein phosphatase 2A phosphorylation regulation
por: Morishita, Kazuhiro, et al.
Publicado: (2020)

Expression of merlin, NDRG2, ERBB2, and c-MYC in meningiomas: relationship with tumor grade and recurrence
por: Ongaratti, B.R., et al.
Publicado: (2016)

Prognostic and biological role of the N-Myc downstream-regulated gene family in hepatocellular carcinoma
por: Yin, Xin, et al.
Publicado: (2022)

N-myc Downstream Regulated Gene 1 Promotes Adipocyte Differentiation in Endothelial Cells of Infantile Hemangioma
por: Lee, Seon Bok, et al.
Publicado: (2023)

The proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1
por: Liu, Wensheng, et al.
Publicado: (2015)

N-myc downstream-regulated gene 2 expression is associated with glucose transport and correlated with prognosis in breast carcinoma
por: Ma, Ji, et al.
Publicado: (2014)

Astroglial N‐myc downstream‐regulated gene 2 protects the brain from cerebral edema induced by stroke
por: Guo, Hang, et al.
Publicado: (2020)

Oncogenic MNK signalling regulates the metastasis suppressor NDRG1
por: Tian, Shuye, et al.
Publicado: (2017)

Regulation of tumor-associated macrophage (TAM) differentiation by NDRG2 expression in breast cancer cells
por: Lee, Soyeon, et al.
Publicado: (2022)

Loss of NDRG2 in liver microenvironment inhibits cancer liver metastasis by regulating tumor associate macrophages polarization
por: Li, Mengyang, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_bedp3hocftfj6ku0cgq6qug4f4