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Hepatocyte Nuclear Factor 1α Proinflammatory Effect Linked to the Overexpression of Liver Nuclear Factor–κB in Experimental Model of Chronic Kidney Disease

Chronic kidney disease (CKD) is associated with low-grade inflammation that activates nuclear factor–κB (NF–κB), which upregulates the expression of numerous NF–κB responsive genes, including the genes encoding IL-6, ICAM-1, VCAM-1, and MCP-1. Herein, we found the coordinated overexpression of genes...

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Detalles Bibliográficos
Autores principales: Sucajtys-Szulc, Elzbieta, Debska-Slizien, Alicja, Rutkowski, Boleslaw, Szolkiewicz, Marek, Swierczynski, Julian, Smolenski, Ryszard Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408856/
https://www.ncbi.nlm.nih.gov/pubmed/36012158
http://dx.doi.org/10.3390/ijms23168883