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Toxic and Phenotypic Effects of AAV_Cre Used to Transduce Mesencephalic Dopaminergic Neurons

A popular approach to spatiotemporally target genes using the loxP/Cre recombination system is stereotaxic microinjection of adeno-associated virus (AAV) expressing Cre recombinase (AAV_Cre) in specific neuronal structures. Here, we report that AAV_Cre microinjection in the ventral tegmental area (V...

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Detalles Bibliográficos
Autores principales: Erben, Larissa, Welday, Jacqueline P., Murphy, Ricardo, Buonanno, Andres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408874/
https://www.ncbi.nlm.nih.gov/pubmed/36012727
http://dx.doi.org/10.3390/ijms23169462

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