Cargando…

TNF-α Affects Signature Cytokines of Th1 and Th17 T Cell Subsets through Differential Actions on TNFR1 and TNFR2

Tumor necrosis factor (TNF)-α is a pleiotropic cytokine implicated in the etiology of several autoimmune diseases, including rheumatoid arthritis (RA). TNF-α regulates diverse effector functions through the activation of TNF-α receptor (TNFR)1 and TNFR2. Although the detrimental role of this cytokin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pesce, Bárbara, Ribeiro, Carolina H., Larrondo, Milton, Ramos, Verónica, Soto, Lilian, Catalán, Diego, Aguillón, Juan Carlos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408897/ https://www.ncbi.nlm.nih.gov/pubmed/36012570 http://dx.doi.org/10.3390/ijms23169306

Ejemplares similares

Transmembrane TNF and Its Receptors TNFR1 and TNFR2 in Mycobacterial Infections
por: Ruiz, Andy, et al.
Publicado: (2021)

Identification of novel inhibitors for TNFα, TNFR1 and TNFα-TNFR1 complex using pharmacophore-based approaches
por: Saddala, Madhu Sudhana, et al.
Publicado: (2019)

Preclinical and clinical aspects of TNF-α and its receptors TNFR1 and TNFR2 in breast cancer
por: Martínez-Reza, Isela, et al.
Publicado: (2017)

Transmembrane TNF and Partially TNFR1 Regulate TNFR2 Expression and Control Inflammation in Mycobacterial-Induced Pleurisy
por: Uysal, Husnu, et al.
Publicado: (2018)

Differential Expression, Shedding, Cytokine Regulation and Function of TNFR1 and TNFR2 in Human Fetal Astrocytes
por: Choi, Sun Ju, et al.
Publicado: (2005)

Activation of TNFR2 sensitizes macrophages for TNFR1-mediated necroptosis
por: Siegmund, Daniela, et al.
Publicado: (2016)

TNFR1 and TNFR2 in the Control of the Life and Death Balance of Macrophages
por: Wajant, Harald, et al.
Publicado: (2019)

Fn14 and TNFR2 as regulators of cytotoxic TNFR1 signaling
por: Siegmund, Daniela, et al.
Publicado: (2023)

Editorial: Targeting TNF/TNFR signaling pathways
por: Pan, Liqiang, et al.
Publicado: (2023)

Co-modulation of TNFR1 and TNFR2 in an animal model of multiple sclerosis
por: Fiedler, Timon, et al.
Publicado: (2023)

Gut region-specific TNFR expression: TNFR2 is more affected than TNFR1 in duodenal myenteric ganglia of diabetic rats
por: Barta, Bence Pál, et al.
Publicado: (2023)

Anti-TNF-α Drugs Differently Affect the TNFα-sTNFR System and Monocyte Subsets in Patients with Psoriasis
por: Gibellini, Lara, et al.
Publicado: (2016)

TACE/ADAM17 substrates associate with ACS (Ep-CAM, HB-EGF) and follow-up MACE (TNFR1 and TNFR2)
por: Chemaly, Melody, et al.
Publicado: (2022)

TNFR1 and TNFR2 regulate the extrinsic apoptotic pathway in myeloma cells by multiple mechanisms
por: Rauert, H, et al.
Publicado: (2011)

TNF-α enhances Th9 cell differentiation and antitumor immunity via TNFR2-dependent pathways
por: Jiang, Yuxue, et al.
Publicado: (2019)

Critical role of TNF-alpha-TNFR1 signaling in intracranial aneurysm formation
por: Aoki, Tomohiro, et al.
Publicado: (2014)

TNF-TNFR1 Signaling Enhances the Protection Against Neospora caninum Infection
por: Ferreira França, Flávia Batista, et al.
Publicado: (2022)

TNFR2 unlocks a RIPK1 kinase activity-dependent mode of proinflammatory TNFR1 signaling
por: Siegmund, Daniela, et al.
Publicado: (2018)

Leukocyte TNFR1 and TNFR2 Expression Contributes to the Peripheral Immune Response in Cases with Ischemic Stroke
por: Hansen, Rikke B., et al.
Publicado: (2021)

Distinct Role of TNFR1 and TNFR2 in Protective Immunity Against Orientia tsutsugamushi Infection in Mice
por: Liang, Yuejin, et al.
Publicado: (2022)

Effects of the SGLT2 inhibitor canagliflozin on plasma biomarkers TNFR-1, TNFR-2 and KIM-1 in the CANVAS trial
por: Sen, Taha, et al.
Publicado: (2021)

Differential roles of TNFα-TNFR1 and TNFα-TNFR2 in the differentiation and function of CD4(+)Foxp3(+) induced Treg cells in vitro and in vivo periphery in autoimmune diseases
por: Yang, Sujuan, et al.
Publicado: (2019)

Structural insights into the disruption of TNF-TNFR1 signalling by small molecules stabilising a distorted TNF
por: McMillan, David, et al.
Publicado: (2021)

TNF-α and TNFR1 responses to recovery therapies following acute resistance exercise
por: Townsend, Jeremy R., et al.
Publicado: (2015)

Poly-ubiquitination in TNFR1-mediated necroptosis
por: Dondelinger, Yves, et al.
Publicado: (2016)

TNFR1-d2 carrying the p.(Thr79Met) pathogenic variant is a potential novel actor of TNFα/TNFR1 signalling regulation in the pathophysiology of TRAPS
por: Rittore, Cécile, et al.
Publicado: (2021)

Precambrian origins of the TNFR superfamily
por: Quistad, S D, et al.
Publicado: (2016)

Differential expression of TNFR1 (CD120a) and TNFR2 (CD120b) on subpopulations of human monocytes
por: Hijdra, Daniëlle, et al.
Publicado: (2012)

Circulating cathepsin-S levels correlate with GFR decline and sTNFR1 and sTNFR2 levels in mice and humans
por: Steubl, Dominik, et al.
Publicado: (2017)

YB-1 Interferes with TNFα–TNFR Binding and Modulates Progranulin-Mediated Inhibition of TNFα Signaling
por: Hessman, Christopher L., et al.
Publicado: (2020)

Contributing role of TNF, IL-10, sTNFR1 and TNF gene polymorphisms in disease severity of leptospirosis
por: Nisansala, Thilini, et al.
Publicado: (2021)

Glucocorticoid-induced microRNA-511 protects against TNF by down-regulating TNFR1
por: Puimège, Leen, et al.
Publicado: (2015)

Anti-inflammatory treatment in MPN: targeting TNFR1 and TNFR2 in JAK2-V617F–induced disease
por: Müller, Peter, et al.
Publicado: (2021)

A TNFR2-Specific TNF Fusion Protein With Improved In Vivo Activity
por: Vargas, Juan Gamboa, et al.
Publicado: (2022)

Alleviation of Ultraviolet-B Radiation-Induced Photoaging by a TNFR Antagonistic Peptide, TNFR2-SKE
por: Lee, Kyoung-Jin, et al.
Publicado: (2019)

The Roles of TNFR2 Signaling in Cancer Cells and the Tumor Microenvironment and the Potency of TNFR2 Targeted Therapy
por: Takahashi, Hiroyuki, et al.
Publicado: (2022)

Inflammatory factor TNF-α promotes the growth of breast cancer via the positive feedback loop of TNFR1/NF-κB (and/or p38)/p-STAT3/HBXIP/TNFR1
por: Cai, Xiaoli, et al.
Publicado: (2017)

TNFR1 single nucleotide polymorphisms are not associated with cervical HPV-induced pre-malignant lesion but regulate in situ cervical TNFR1 expression
por: da Rocha, Natália Pereira, et al.
Publicado: (2019)

Genetic Knock-out of TNFR1 and TNFR2 in a JAK2-V617F Polycythemia Vera Mouse Model
por: Müller, Peter, et al.
Publicado: (2022)

Sequential treatment with a TNFR2 agonist and a TNFR1 antagonist improves outcomes in a humanized mouse model for MS
por: Pegoretti, Valentina, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_f401a7bq5jbotsoik7q3fm4mia