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Recombinant Adeno-Associated Viral Vector-Mediated Gene Transfer of hTBX18 Generates Pacemaker Cells from Ventricular Cardiomyocytes

Sinoatrial node dysfunction can manifest as bradycardia, leading to symptoms of syncope and sudden cardiac death. Electronic pacemakers are the current standard of care but are limited due to a lack of biological chronotropic control, cost of revision surgeries, and risk of lead- and device-related...

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Detalles Bibliográficos
Autores principales:	Farraha, Melad, Rao, Renuka, Igoor, Sindhu, Le, Thi Y. L., Barry, Michael A., Davey, Christopher, Kok, Cindy, Chong, James J.H., Kizana, Eddy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408910/ https://www.ncbi.nlm.nih.gov/pubmed/36012498 http://dx.doi.org/10.3390/ijms23169230

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