Epigenetic Regulation of Optic Nerve Development, Protection, and Repair

Epigenetic factors are known to influence tissue development, functionality, and their response to pathophysiology. This review will focus on different types of epigenetic regulators and their associated molecular apparatus that affect the optic nerve. A comprehensive understanding of epigenetic reg...

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Autores principales: Ashok, Ajay, Pooranawattanakul, Sarita, Tai, Wai Lydia, Cho, Kin-Sang, Utheim, Tor P., Cestari, Dean M., Chen, Dong Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408916/
https://www.ncbi.nlm.nih.gov/pubmed/36012190
http://dx.doi.org/10.3390/ijms23168927
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author Ashok, Ajay
Pooranawattanakul, Sarita
Tai, Wai Lydia
Cho, Kin-Sang
Utheim, Tor P.
Cestari, Dean M.
Chen, Dong Feng
author_facet Ashok, Ajay
Pooranawattanakul, Sarita
Tai, Wai Lydia
Cho, Kin-Sang
Utheim, Tor P.
Cestari, Dean M.
Chen, Dong Feng
author_sort Ashok, Ajay
collection PubMed
description Epigenetic factors are known to influence tissue development, functionality, and their response to pathophysiology. This review will focus on different types of epigenetic regulators and their associated molecular apparatus that affect the optic nerve. A comprehensive understanding of epigenetic regulation in optic nerve development and homeostasis will help us unravel novel molecular pathways and pave the way to design blueprints for effective therapeutics to address optic nerve protection, repair, and regeneration.
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spelling pubmed-94089162022-08-26 Epigenetic Regulation of Optic Nerve Development, Protection, and Repair Ashok, Ajay Pooranawattanakul, Sarita Tai, Wai Lydia Cho, Kin-Sang Utheim, Tor P. Cestari, Dean M. Chen, Dong Feng Int J Mol Sci Review Epigenetic factors are known to influence tissue development, functionality, and their response to pathophysiology. This review will focus on different types of epigenetic regulators and their associated molecular apparatus that affect the optic nerve. A comprehensive understanding of epigenetic regulation in optic nerve development and homeostasis will help us unravel novel molecular pathways and pave the way to design blueprints for effective therapeutics to address optic nerve protection, repair, and regeneration. MDPI 2022-08-10 /pmc/articles/PMC9408916/ /pubmed/36012190 http://dx.doi.org/10.3390/ijms23168927 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ashok, Ajay
Pooranawattanakul, Sarita
Tai, Wai Lydia
Cho, Kin-Sang
Utheim, Tor P.
Cestari, Dean M.
Chen, Dong Feng
Epigenetic Regulation of Optic Nerve Development, Protection, and Repair
title Epigenetic Regulation of Optic Nerve Development, Protection, and Repair
title_full Epigenetic Regulation of Optic Nerve Development, Protection, and Repair
title_fullStr Epigenetic Regulation of Optic Nerve Development, Protection, and Repair
title_full_unstemmed Epigenetic Regulation of Optic Nerve Development, Protection, and Repair
title_short Epigenetic Regulation of Optic Nerve Development, Protection, and Repair
title_sort epigenetic regulation of optic nerve development, protection, and repair
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408916/
https://www.ncbi.nlm.nih.gov/pubmed/36012190
http://dx.doi.org/10.3390/ijms23168927
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