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SIRT7 Deficiency Protects against Aβ(42)-Induced Apoptosis through the Regulation of NOX4-Derived Reactive Oxygen Species Production in SH-SY5Y Cells

Alzheimer’s disease (AD) is an age-related neurodegenerative disease that is characterized by irreversible memory loss and cognitive decline. The deposition of amyloid-β (Aβ), especially aggregation-prone Aβ(42), is considered to be an early event preceding neurodegeneration in AD. Sirtuins (SIRT1–7...

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Detalles Bibliográficos
Autores principales:	Mizutani, Hironori, Sato, Yoshifumi, Yamazaki, Masaya, Yoshizawa, Tatsuya, Ando, Yukio, Ueda, Mitsuharu, Yamagata, Kazuya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408927/ https://www.ncbi.nlm.nih.gov/pubmed/36012298 http://dx.doi.org/10.3390/ijms23169027

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