Cargando…

The Relevance of Crystal Forms in the Pharmaceutical Field: Sword of Damocles or Innovation Tools?

This review is aimed to provide to an “educated but non-expert” readership and an overview of the scientific, commercial, and ethical importance of investigating the crystalline forms (polymorphs, hydrates, and co-crystals) of active pharmaceutical ingredients (API). The existence of multiple crysta...

Descripción completa

Detalles Bibliográficos
Autores principales:	Braga, Dario, Casali, Lucia, Grepioni, Fabrizia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408954/ https://www.ncbi.nlm.nih.gov/pubmed/36012275 http://dx.doi.org/10.3390/ijms23169013

Ejemplares similares

Reperfusing the myocardium - a damocles Sword
por: Shah, V.K., et al.
Publicado: (2018)

The sword of Damocles for the splenectomised: death by OPSI
por: Blumentrath, Christian Georg, et al.
Publicado: (2016)

Obesity and Diabetes: A Sword of Damocles for Future Generations
por: Angi, Alessia, et al.
Publicado: (2020)

Artificial intelligence, capsule endoscopy, databases, and the Sword of Damocles
por: Dray, Xavier, et al.
Publicado: (2021)

Making crystals with a purpose; a journey in crystal engineering at the University of Bologna
por: Braga, Dario, et al.
Publicado: (2017)

Exploring the Co-Crystallization of Kojic Acid with Silver(I), Copper(II), Zinc(II), and Gallium(III) for Potential Antibacterial Applications
por: Sun, Renren, et al.
Publicado: (2023)

NATO Advanced Study Institute on Crystal Engineering : From Molecules and Crystals to Materials
por: Braga, Dario, et al.
Publicado: (1999)

Hemodialysis—Nutritional Flaws in Diagnosis and Prescriptions. Could Amino Acid Losses Be the Sharpest “Sword of Damocles”?
por: Bolasco, Piergiorgio
Publicado: (2020)

Disease Recurrence—The Sword of Damocles in Kidney Transplantation for Primary Focal Segmental Glomerulosclerosis
por: Kienzl-Wagner, Katrin, et al.
Publicado: (2019)

Low-Dose Acetylsalicylic Acid in Chronic Subdural Hematomas: A Neurosurgeon's Sword of Damocles
por: Mongardi, Lorenzo, et al.
Publicado: (2020)

Searching for Suitable Kojic Acid Coformers: From Cocrystals and Salt to Eutectics
por: Sun, Renren, et al.
Publicado: (2023)

Plasmodium falciparum resistance to artemisinin-based combination therapies: A sword of Damocles in the path toward malaria elimination
por: Ouji, Manel, et al.
Publicado: (2018)

Overwork-Induced Sudden Death: A Sword of Damocles Hanging over Chinese Medical Staff
por: YANG, Ce, et al.
Publicado: (2020)

Managing the “Sword of Damocles” of Immunosuppression: Prevention, Early Diagnosis, and Treatment of Infectious Diseases in Kidney Transplantation
por: Cacciola, Roberto, et al.
Publicado: (2023)

Co-crystallization of antibacterials with inorganic salts: paving the way to activity enhancement
por: Shemchuk, Oleksii, et al.
Publicado: (2020)

Management of a Mobile Floating Carotid Plaque Responsible for Calcified Cerebral Emboli: A Double Sword of Damocles
por: Sénémaud, Jean, et al.
Publicado: (2021)

Comparison of Antimicrobial and Antibiofilm Activity of Proflavine Co-crystallized with Silver, Copper, Zinc, and Gallium Salts
por: Lekhan, Andrii, et al.
Publicado: (2022)

‘A sword of Damocles’: patient and caregiver beliefs, attitudes and perspectives on presymptomatic testing for autosomal dominant polycystic kidney disease: a focus group study
por: Logeman, Charlotte, et al.
Publicado: (2020)

Sword of Damocles: application of the ethical principles of resource allocation to essential cancer surgery patients requiring beds in limited supply during the COVID-19 pandemic
por: Al-Benna, Sammy
Publicado: (2020)

La espada de Damocles : la crisis en Grecia y el destino de Europa /
por: Markaris, Petros
Publicado: (2012)

Antimicrobial activity of supramolecular salts of gallium(III) and proflavine and the intriguing case of a trioxalate complex
por: Guerrini, Marzia, et al.
Publicado: (2022)

The Role of Ionic Liquids in the Pharmaceutical Field: An Overview of Relevant Applications
por: Pedro, Sónia N., et al.
Publicado: (2020)

Outcomes of Sword Swallowing and Pharmaceutical Step-Therapy Interventions
por: Curtiss, Frederic R.
Publicado: (2007)

Crystal forms in pharmaceutical applications: olanzapine, a gift to crystal chemistry that keeps on giving
por: Reutzel-Edens, Susan M., et al.
Publicado: (2020)

The Development of Innovative Dosage Forms of the Fixed-Dose Combination of Active Pharmaceutical Ingredients
por: Janczura, Magdalena, et al.
Publicado: (2022)

Mechanochemical Preparation, Solid-State Characterization, and Antimicrobial Performance of Copper and Silver Nitrate Coordination Polymers with L- and DL-Arginine and Histidine
por: Fiore, Cecilia, et al.
Publicado: (2023)

Our Field, and the Two-edge Sword
por: Abdulrauf, Badr M. I.
Publicado: (2023)

Scalpel and Sword
Publicado: (1937)

Enhanced NMR Discrimination of Pharmaceutically Relevant Molecular Crystal Forms through Fragment-Based Ab Initio Chemical Shift Predictions
por: Hartman, Joshua D., et al.
Publicado: (2016)

Image Analysis: A Versatile Tool in the Manufacturing and Quality Control of Pharmaceutical Dosage Forms
por: Farkas, Dóra, et al.
Publicado: (2021)

The Double-Edged Sword Effect of Abusive Supervision on Subordinates’ Innovative Behavior
por: Zhu, Jinqiang, et al.
Publicado: (2019)

Crystallization Tendency of Pharmaceutical Glasses: Relevance to Compound Properties, Impact of Formulation Process, and Implications for Design of Amorphous Solid Dispersions
por: Kawakami, Kohsaku
Publicado: (2019)

Karyotype reinvestigation does not confirm the presence of two cryptic species and interspecific hybridization in the Polyommatus (Agrodiaetus) damocles complex in the Crimea (Lepidoptera, Lycaenidae)
por: Lukhtanov, Vladimir A., et al.
Publicado: (2019)

Social pharmaceutical innovation and alternative forms of research, development and deployment for drugs for rare diseases
por: Douglas, Conor M. W., et al.
Publicado: (2022)

Curcumin: Biological Activities and Modern Pharmaceutical Forms
por: Urošević, Maja, et al.
Publicado: (2022)

EVITA: a tool for the early EValuation of pharmaceutical Innovations with regard to Therapeutic Advantage
por: Püntmann, Isabel, et al.
Publicado: (2010)

Use of an Innovative Pharmaceutical Class Scoring Tool for Prioritized Annual Formulary Review
por: Sheldon, Holly, et al.
Publicado: (2022)

Regioselective functionalization of aryl azoles as powerful tool for the synthesis of pharmaceutically relevant targets
por: Lutter, Ferdinand H., et al.
Publicado: (2020)

Materials for Pharmaceutical Dosage Forms: Molecular Pharmaceutics and Controlled Release Drug Delivery Aspects
por: Mansour, Heidi M., et al.
Publicado: (2010)

Sample Preparation of Posaconazole Oral Suspensions for Identification of the Crystal Form of the Active Pharmaceutical Ingredient
por: Lykouras, Michail, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_1pjbvtk5mm1emhfhpoq95bn164