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New, Fully Implantable Device for Selective Clearance of CSF-Target Molecules: Proof of Concept in a Murine Model of Alzheimer’s Disease

We have previously proposed a radical change in the current strategy to clear pathogenic proteins from the central nervous system (CNS) based on the cerebrospinal fluid (CSF)-sink therapeutic strategy, whereby pathogenic proteins can be removed directly from the CNS via CSF. To this aim, we designed...

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Detalles Bibliográficos
Autores principales:	Coto-Vilcapoma, María Almudena, Castilla-Silgado, Juan, Fernández-García, Benjamín, Pinto-Hernández, Paola, Cipriani, Raffaela, Capetillo-Zarate, Estibaliz, Menéndez-González, Manuel, Álvarez-Vega, Marco, Tomás-Zapico, Cristina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408974/ https://www.ncbi.nlm.nih.gov/pubmed/36012525 http://dx.doi.org/10.3390/ijms23169256

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